Sage EH - Search Results

1

Compromised production of extracellular matrix in mice lacking secreted protein, acidic and rich in cysteine (SPARC) leads to a reduced foreign body reaction to implanted biomaterials.

Puolakkainen P, Bradshaw AD, Kyriakides TR, Reed M, Brekken R, Wight T, Bornstein P, Ratner B, Sage EH. Puolakkainen P, et al. Among authors: sage eh. Am J Pathol. 2003 Feb;162(2):627-35. doi: 10.1016/S0002-9440(10)63856-4. Am J Pathol. 2003. PMID: 12547720 Free PMC article.

2

SPARC-null mice exhibit accelerated cutaneous wound closure.

Bradshaw AD, Reed MJ, Sage EH. Bradshaw AD, et al. Among authors: sage eh. J Histochem Cytochem. 2002 Jan;50(1):1-10. doi: 10.1177/002215540205000101. J Histochem Cytochem. 2002. PMID: 11748289

3

Enhanced growth of tumors in SPARC null mice is associated with changes in the ECM.

Brekken RA, Puolakkainen P, Graves DC, Workman G, Lubkin SR, Sage EH. Brekken RA, et al. Among authors: sage eh. J Clin Invest. 2003 Feb;111(4):487-95. doi: 10.1172/JCI16804. J Clin Invest. 2003. PMID: 12588887 Free PMC article.

4

Enhanced growth of pancreatic tumors in SPARC-null mice is associated with decreased deposition of extracellular matrix and reduced tumor cell apoptosis.

Puolakkainen PA, Brekken RA, Muneer S, Sage EH. Puolakkainen PA, et al. Among authors: sage eh. Mol Cancer Res. 2004 Apr;2(4):215-24. Mol Cancer Res. 2004. PMID: 15140943

5

Matricellular homologs in the foreign body response: hevin suppresses inflammation, but hevin and SPARC together diminish angiogenesis.

Barker TH, Framson P, Puolakkainen PA, Reed M, Funk SE, Sage EH. Barker TH, et al. Among authors: sage eh. Am J Pathol. 2005 Mar;166(3):923-33. doi: 10.1016/S0002-9440(10)62312-7. Am J Pathol. 2005. PMID: 15743803 Free PMC article.

6

Reduced foreign body reaction to implanted biomaterials by surface treatment with oriented osteopontin.

Liu L, Chen G, Chao T, Ratner BD, Sage EH, Jiang S. Liu L, et al. Among authors: sage eh. J Biomater Sci Polym Ed. 2008;19(6):821-35. doi: 10.1163/156856208784522083. J Biomater Sci Polym Ed. 2008. PMID: 18534099

7

Alterations in the lens capsule contribute to cataractogenesis in SPARC-null mice.

Yan Q, Clark JI, Wight TN, Sage EH. Yan Q, et al. Among authors: sage eh. J Cell Sci. 2002 Jul 1;115(Pt 13):2747-56. doi: 10.1242/jcs.115.13.2747. J Cell Sci. 2002. PMID: 12077365

8

Cleavage of the matricellular protein SPARC by matrix metalloproteinase 3 produces polypeptides that influence angiogenesis.

Sage EH, Reed M, Funk SE, Truong T, Steadele M, Puolakkainen P, Maurice DH, Bassuk JA. Sage EH, et al. J Biol Chem. 2003 Sep 26;278(39):37849-57. doi: 10.1074/jbc.M302946200. Epub 2003 Jul 16. J Biol Chem. 2003. PMID: 12867428 Free article.

9

Functional analysis of the matricellular protein SPARC with novel monoclonal antibodies.

Sweetwyne MT, Brekken RA, Workman G, Bradshaw AD, Carbon J, Siadak AW, Murri C, Sage EH. Sweetwyne MT, et al. Among authors: sage eh. J Histochem Cytochem. 2004 Jun;52(6):723-33. doi: 10.1369/jhc.3A6153.2004. J Histochem Cytochem. 2004. PMID: 15150281

10

Expression and characterization of murine hevin (SC1), a member of the SPARC family of matricellular proteins.

Brekken RA, Sullivan MM, Workman G, Bradshaw AD, Carbon J, Siadak A, Murri C, Framson PE, Sage EH. Brekken RA, et al. Among authors: sage eh. J Histochem Cytochem. 2004 Jun;52(6):735-48. doi: 10.1369/jhc.3A6245.2004. J Histochem Cytochem. 2004. PMID: 15150282

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