Walker EA - Search Results

1

The aldo-keto reductase AKR1C3 is a novel suppressor of cell differentiation that provides a plausible target for the non-cyclooxygenase-dependent antineoplastic actions of nonsteroidal anti-inflammatory drugs.

Desmond JC, Mountford JC, Drayson MT, Walker EA, Hewison M, Ride JP, Luong QT, Hayden RE, Vanin EF, Bunce CM. Desmond JC, et al. Among authors: walker ea. Cancer Res. 2003 Jan 15;63(2):505-12. Cancer Res. 2003. PMID: 12543809

2

A switch in dehydrogenase to reductase activity of 11 beta-hydroxysteroid dehydrogenase type 1 upon differentiation of human omental adipose stromal cells.

Bujalska IJ, Walker EA, Hewison M, Stewart PM. Bujalska IJ, et al. Among authors: walker ea. J Clin Endocrinol Metab. 2002 Mar;87(3):1205-10. doi: 10.1210/jcem.87.3.8301. J Clin Endocrinol Metab. 2002. PMID: 11889189

3

11Beta-hydroxysteroid dehydrogenase type 1 in differentiating omental human preadipocytes: from de-activation to generation of cortisol.

Bujalska IJ, Walker EA, Tomlinson JW, Hewison M, Stewart PM. Bujalska IJ, et al. Among authors: walker ea. Endocr Res. 2002 Nov;28(4):449-61. doi: 10.1081/erc-120016822. Endocr Res. 2002. PMID: 12530648

4

Prereceptor regulation of glucocorticoid action by 11beta-hydroxysteroid dehydrogenase: a novel determinant of cell proliferation.

Rabbitt EH, Lavery GG, Walker EA, Cooper MS, Stewart PM, Hewison M. Rabbitt EH, et al. Among authors: walker ea. FASEB J. 2002 Jan;16(1):36-44. doi: 10.1096/fj.01-0582com. FASEB J. 2002. PMID: 11772934

5

Cortisone-reductase deficiency associated with heterozygous mutations in 11beta-hydroxysteroid dehydrogenase type 1.

Lawson AJ, Walker EA, Lavery GG, Bujalska IJ, Hughes B, Arlt W, Stewart PM, Ride JP. Lawson AJ, et al. Among authors: walker ea. Proc Natl Acad Sci U S A. 2011 Mar 8;108(10):4111-6. doi: 10.1073/pnas.1014934108. Epub 2011 Feb 15. Proc Natl Acad Sci U S A. 2011. PMID: 21325058 Free PMC article.

6

Functional expression, characterization, and purification of the catalytic domain of human 11-beta -hydroxysteroid dehydrogenase type 1.

Walker EA, Clark AM, Hewison M, Ride JP, Stewart PM. Walker EA, et al. J Biol Chem. 2001 Jun 15;276(24):21343-50. doi: 10.1074/jbc.M011142200. Epub 2001 Apr 6. J Biol Chem. 2001. PMID: 11294832 Free article.

7

Mutations of key hydrophobic surface residues of 11 beta-hydroxysteroid dehydrogenase type 1 increase solubility and monodispersity in a bacterial expression system.

Lawson AJ, Walker EA, White SA, Dafforn TR, Stewart PM, Ride JP. Lawson AJ, et al. Among authors: walker ea. Protein Sci. 2009 Jul;18(7):1552-63. doi: 10.1002/pro.150. Protein Sci. 2009. PMID: 19507261 Free PMC article.

8

Serum- and glucocorticoid-regulated kinase isoform-1 and epithelial sodium channel subunits in human ocular ciliary epithelium.

Rauz S, Walker EA, Hughes SV, Coca-Prados M, Hewison M, Murray PI, Stewart PM. Rauz S, et al. Among authors: walker ea. Invest Ophthalmol Vis Sci. 2003 Apr;44(4):1643-51. doi: 10.1167/iovs.02-0514. Invest Ophthalmol Vis Sci. 2003. PMID: 12657604

9

Constitutive expression of 25-hydroxyvitamin D3-1alpha-hydroxylase in a transformed human proximal tubule cell line: evidence for direct regulation of vitamin D metabolism by calcium.

Bland R, Walker EA, Hughes SV, Stewart PM, Hewison M. Bland R, et al. Among authors: walker ea. Endocrinology. 1999 May;140(5):2027-34. doi: 10.1210/endo.140.5.6683. Endocrinology. 1999. PMID: 10218951

10

Expression of 11 beta-hydroxysteroid dehydrogenase isozymes and corticosteroid hormone receptors in primary cultures of human trophoblast and placental bed biopsies.

Driver PM, Kilby MD, Bujalska I, Walker EA, Hewison M, Stewart PM. Driver PM, et al. Among authors: walker ea. Mol Hum Reprod. 2001 Apr;7(4):357-63. doi: 10.1093/molehr/7.4.357. Mol Hum Reprod. 2001. PMID: 11279298

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