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Page 1
Pin1: a therapeutic target in Alzheimer neurodegeneration.
Hamdane M, Smet C, Sambo AV, Leroy A, Wieruszeski JM, Delobel P, Maurage CA, Ghestem A, Wintjens R, Bégard S, Sergeant N, Delacourte A, Horvath D, Landrieu I, Lippens G, Buée L. Hamdane M, et al. Among authors: sambo av. J Mol Neurosci. 2002 Dec;19(3):275-87. doi: 10.1385/JMN:19:3:275. J Mol Neurosci. 2002. PMID: 12540053
Abnormal Tau phosphorylation of the Alzheimer-type also occurs during mitosis.
Delobel P, Flament S, Hamdane M, Mailliot C, Sambo AV, Bégard S, Sergeant N, Delacourte A, Vilain JP, Buée L. Delobel P, et al. Among authors: sambo av. J Neurochem. 2002 Oct;83(2):412-20. doi: 10.1046/j.1471-4159.2002.01143.x. J Neurochem. 2002. PMID: 12423251 Free article.
Pin1 allows for differential Tau dephosphorylation in neuronal cells.
Hamdane M, Dourlen P, Bretteville A, Sambo AV, Ferreira S, Ando K, Kerdraon O, Bégard S, Geay L, Lippens G, Sergeant N, Delacourte A, Maurage CA, Galas MC, Buée L. Hamdane M, et al. Among authors: sambo av. Mol Cell Neurosci. 2006 May-Jun;32(1-2):155-60. doi: 10.1016/j.mcn.2006.03.006. Epub 2006 May 11. Mol Cell Neurosci. 2006. PMID: 16697218
Tau pathology modulates Pin1 post-translational modifications and may be relevant as biomarker.
Ando K, Dourlen P, Sambo AV, Bretteville A, Bélarbi K, Vingtdeux V, Eddarkaoui S, Drobecq H, Ghestem A, Bégard S, Demey-Thomas E, Melnyk P, Smet C, Lippens G, Maurage CA, Caillet-Boudin ML, Verdier Y, Vinh J, Landrieu I, Galas MC, Blum D, Hamdane M, Sergeant N, Buée L. Ando K, et al. Among authors: sambo av. Neurobiol Aging. 2013 Mar;34(3):757-69. doi: 10.1016/j.neurobiolaging.2012.08.004. Epub 2012 Aug 25. Neurobiol Aging. 2013. PMID: 22926167
Mitotic-like tau phosphorylation by p25-Cdk5 kinase complex.
Hamdane M, Sambo AV, Delobel P, Bégard S, Violleau A, Delacourte A, Bertrand P, Benavides J, Buée L. Hamdane M, et al. Among authors: sambo av. J Biol Chem. 2003 Sep 5;278(36):34026-34. doi: 10.1074/jbc.M302872200. Epub 2003 Jun 24. J Biol Chem. 2003. PMID: 12826674 Free article.
12 results