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Page 1
Preparation and reactivity of O2-sulfonated diazeniumdiolates.
D'Sa RA, Wang Y, Ruane PH, Showalter BM, Saavedra JE, Davies KM, Citro ML, Booth MN, Keefer LK, Toscano JP. D'Sa RA, et al. Among authors: saavedra je. J Org Chem. 2003 Jan 24;68(2):656-7. doi: 10.1021/jo026656n. J Org Chem. 2003. PMID: 12530906
Hydrolytic reactivity trends among potential prodrugs of the O2-glycosylated diazeniumdiolate family. Targeting nitric oxide to macrophages for antileishmanial activity.
Valdez CA, Saavedra JE, Showalter BM, Davies KM, Wilde TC, Citro ML, Barchi JJ Jr, Deschamps JR, Parrish D, El-Gayar S, Schleicher U, Bogdan C, Keefer LK. Valdez CA, et al. Among authors: saavedra je. J Med Chem. 2008 Jul 10;51(13):3961-70. doi: 10.1021/jm8000482. Epub 2008 Jun 6. J Med Chem. 2008. PMID: 18533711 Free PMC article.
Chemistry of the diazeniumdiolates: Z right harpoon over left harpoon E isomerism.
Wang YN, Bohle DS, Bonifant CL, Chmurny GN, Collins JR, Davies KM, Deschamps J, Flippen-Anderson JL, Keefer LK, Klose JR, Saavedra JE, Waterhouse DJ, Ivanic J. Wang YN, et al. Among authors: saavedra je. J Am Chem Soc. 2005 Apr 20;127(15):5388-95. doi: 10.1021/ja042258l. J Am Chem Soc. 2005. PMID: 15826177
V-PROLI/NO, a prodrug of the nitric oxide donor, PROLI/NO.
Chakrapani H, Showalter BM, Kong L, Keefer LK, Saavedra JE. Chakrapani H, et al. Among authors: saavedra je. Org Lett. 2007 Aug 16;9(17):3409-12. doi: 10.1021/ol701419a. Epub 2007 Jul 20. Org Lett. 2007. PMID: 17658755
Glycosylated PROLI/NO derivatives as nitric oxide prodrugs.
Nandurdikar RS, Maciag AE, Hong SY, Chakrapani H, Citro ML, Keefer LK, Saavedra JE. Nandurdikar RS, et al. Among authors: saavedra je. Org Lett. 2010 Jan 1;12(1):56-9. doi: 10.1021/ol902481s. Org Lett. 2010. PMID: 19954198 Free PMC article.
166 results