Gainsford GJ - Search Results

1

8-Aza-immucillins as transition-state analogue inhibitors of purine nucleoside phosphorylase and nucleoside hydrolases.

Evans GB, Furneaux RH, Gainsford GJ, Hanson JC, Kicska GA, Sauve AA, Schramm VL, Tyler PC. Evans GB, et al. Among authors: gainsford gj. J Med Chem. 2003 Jan 2;46(1):155-60. doi: 10.1021/jm0203332. J Med Chem. 2003. PMID: 12502369

2

A beta-fluoroamine inhibitor of purine nucleoside phosphorylase.

Mason JM, Murkin AS, Li L, Schramm VL, Gainsford GJ, Skelton BW. Mason JM, et al. Among authors: gainsford gj. J Med Chem. 2008 Sep 25;51(18):5880-4. doi: 10.1021/jm800792b. J Med Chem. 2008. PMID: 18800772 Free PMC article.

3

The synthesis and antibacterial activity of totarol derivatives. Part 3: Modification of ring-B.

Evans GB, Furneaux RH, Gainsford GJ, Murphy MP. Evans GB, et al. Among authors: gainsford gj. Bioorg Med Chem. 2000 Jul;8(7):1663-75. doi: 10.1016/s0968-0896(00)00096-1. Bioorg Med Chem. 2000. PMID: 10976514

4

Transition state structure of purine nucleoside phosphorylase and principles of atomic motion in enzymatic catalysis.

Fedorov A, Shi W, Kicska G, Fedorov E, Tyler PC, Furneaux RH, Hanson JC, Gainsford GJ, Larese JZ, Schramm VL, Almo SC. Fedorov A, et al. Among authors: gainsford gj. Biochemistry. 2001 Jan 30;40(4):853-60. doi: 10.1021/bi002499f. Biochemistry. 2001. PMID: 11170405

5

A synchrotron radiation study of the one-dimensional complex of sodium with (1S)-N-carboxylato-1-(9-deazaadenin-9-yl)-1,4-dideoxy-1,4-imino-D-ribitol, a member of the 'immucillin' family.

Gainsford GJ, Furneaux RH, Tyler PC, Sauve A, Shramm VL. Gainsford GJ, et al. Acta Crystallogr C. 2010 Mar;66(Pt 3):m65-8. doi: 10.1107/S0108270110002738. Epub 2010 Feb 3. Acta Crystallogr C. 2010. PMID: 20203397 Free PMC article.

6

Bis[(1S)-1,4-azanediyl-1-(9-deazaadenin-9-yl)-1,4-dideoxy-5-methylsulfanyl-D-ribitol] tetrakis(hydrochloride) monohydrate: structure, DFT energy and ligand docking results of a potent methylthioadenosine phosphorylase inhibitor found in different molecular conformations.

Gainsford GJ, Evans GB, Johnston KA, Seth M. Gainsford GJ, et al. Acta Crystallogr C. 2010 Nov;66(Pt 11):o527-30. doi: 10.1107/S0108270110037121. Epub 2010 Oct 8. Acta Crystallogr C. 2010. PMID: 21051818

7

Alkyl 4-chlorobenzoyloxycarbamates as highly effective nitrogen source reagents for the base-free, intermolecular aminohydroxylation reaction.

Harris L, Mee SP, Furneaux RH, Gainsford GJ, Luxenburger A. Harris L, et al. Among authors: gainsford gj. J Org Chem. 2011 Jan 21;76(2):358-72. doi: 10.1021/jo1018816. Epub 2010 Dec 29. J Org Chem. 2011. PMID: 21190319

8

Translationally related nearly identical molecules: 4-methoxyphenyl 4-O-[6-O-acetyl-2-azido-3-O-benzyl-2-deoxy-4-O-(fluoren-9-ylmethoxycarbonyl)-α-D-glucopyranosyl]-2-O-benzoyl-3-O-benzyl-6-O-chloroacetyl-β-D-glucopyranoside.

Gainsford GJ, Schwörer R, Tyler PC. Gainsford GJ, et al. Acta Crystallogr C. 2013 Jun;69(Pt 6):679-82. doi: 10.1107/S010827011301367X. Epub 2013 May 29. Acta Crystallogr C. 2013. PMID: 23744395

9

The chemistry of castanospermine. Direct oxidation of the tetraacetate to the corresponding gamma-lactam.

Furneaux RH, Gainsford GJ, Mason JM, Tyler PC. Furneaux RH, et al. Among authors: gainsford gj. Carbohydr Res. 2004 Jul 12;339(10):1747-51. doi: 10.1016/j.carres.2004.05.006. Carbohydr Res. 2004. PMID: 15220084

10

Synthesis of the enantiomers of hexahydrodibenz[d,f]azecines.

Furneaux RH, Gainsford GJ, Mason JM. Furneaux RH, et al. Among authors: gainsford gj. J Org Chem. 2004 Oct 29;69(22):7665-71. doi: 10.1021/jo049157q. J Org Chem. 2004. PMID: 15497995

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