Seidel A - Search Results

1

DNA adduct formation by the ubiquitous environmental pollutant 3-nitrobenzanthrone and its metabolites in rats.

Arlt VM, Sorg BL, Osborne M, Hewer A, Seidel A, Schmeiser HH, Phillips DH. Arlt VM, et al. Among authors: seidel a. Biochem Biophys Res Commun. 2003 Jan 3;300(1):107-14. doi: 10.1016/s0006-291x(02)02789-4. Biochem Biophys Res Commun. 2003. PMID: 12480528

2

Activation of 3-nitrobenzanthrone and its metabolites by human acetyltransferases, sulfotransferases and cytochrome P450 expressed in Chinese hamster V79 cells.

Arlt VM, Glatt H, Muckel E, Pabel U, Sorg BL, Seidel A, Frank H, Schmeiser HH, Phillips DH. Arlt VM, et al. Among authors: seidel a. Int J Cancer. 2003 Jul 10;105(5):583-92. doi: 10.1002/ijc.11143. Int J Cancer. 2003. PMID: 12740904

3

The impact of p53 on DNA damage and metabolic activation of the environmental carcinogen benzo[a]pyrene: effects in Trp53(+/+), Trp53(+/-) and Trp53(-/-) mice.

Krais AM, Speksnijder EN, Melis JP, Indra R, Moserova M, Godschalk RW, van Schooten FJ, Seidel A, Kopka K, Schmeiser HH, Stiborova M, Phillips DH, Luijten M, Arlt VM. Krais AM, et al. Among authors: seidel a. Arch Toxicol. 2016 Apr;90(4):839-51. doi: 10.1007/s00204-015-1531-8. Epub 2015 May 21. Arch Toxicol. 2016. PMID: 25995008 Free PMC article.

4

Relationship between mutagenicity and DNA adduct formation in mammalian cells for fjord- and bay-region diol-epoxides of polycyclic aromatic hydrocarbons.

Phillips DH, Hewer A, Seidel A, Steinbrecher T, Schrode R, Oesch F, Glatt H. Phillips DH, et al. Among authors: seidel a. Chem Biol Interact. 1991;80(2):177-86. doi: 10.1016/0009-2797(91)90023-z. Chem Biol Interact. 1991. PMID: 1934148

5

Covalent DNA adducts formed in mouse epidermis by benzo[g]chrysene.

Giles AS, Seidel A, Phillips DH. Giles AS, et al. Among authors: seidel a. Carcinogenesis. 1996 Jun;17(6):1331-6. doi: 10.1093/carcin/17.6.1331. Carcinogenesis. 1996. PMID: 8681451

6

Covalent DNA adducts formed by benzo[c]chrysene in mouse epidermis and by benzo[c]chrysene fjord-region diol epoxides reacted with DNA and polynucleotides.

Giles AS, Seidel A, Phillips DH. Giles AS, et al. Among authors: seidel a. Chem Res Toxicol. 1997 Nov;10(11):1275-84. doi: 10.1021/tx970114x. Chem Res Toxicol. 1997. PMID: 9403182

7

Carcinogenic polycyclic aromatic hydrocarbons induce CYP1A1 in human cells via a p53-dependent mechanism.

Wohak LE, Krais AM, Kucab JE, Stertmann J, Øvrebø S, Seidel A, Phillips DH, Arlt VM. Wohak LE, et al. Among authors: seidel a. Arch Toxicol. 2016 Feb;90(2):291-304. doi: 10.1007/s00204-014-1409-1. Epub 2014 Nov 15. Arch Toxicol. 2016. PMID: 25398514 Free PMC article.

8

In vitro reaction with DNA of the fjord-region diol epoxides of benzo[g]chrysene and benzo[c]phenanthrene as studied by 32P-postlabeling.

Giles AS, Seidel A, Phillips DH. Giles AS, et al. Among authors: seidel a. Chem Res Toxicol. 1995 Jun;8(4):591-9. doi: 10.1021/tx00046a014. Chem Res Toxicol. 1995. PMID: 7548740

9

Role of Human Aldo-Keto Reductases in the Metabolic Activation of the Carcinogenic Air Pollutant 3-Nitrobenzanthrone.

Murray JR, Mesaros CA, Arlt VM, Seidel A, Blair IA, Penning TM. Murray JR, et al. Among authors: seidel a. Chem Res Toxicol. 2018 Nov 19;31(11):1277-1288. doi: 10.1021/acs.chemrestox.8b00250. Epub 2018 Nov 8. Chem Res Toxicol. 2018. PMID: 30406992 Free PMC article.

10

Activating mutations in human c-Ha-ras-1 protooncogene induced by stereoisomeric fjord-region benzo[c]chrysene diol-epoxides.

Du MQ, Seidel A, Phillips DH. Du MQ, et al. Among authors: seidel a. Mol Carcinog. 1995 Nov;14(3):160-9. doi: 10.1002/mc.2940140305. Mol Carcinog. 1995. PMID: 7576108

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