Wang QC - Search Results

1

Targeted therapy against human lung cancer in nude mice by high-affinity recombinant antimesothelin single-chain Fv immunotoxin.

Fan D, Yano S, Shinohara H, Solorzano C, Van Arsdall M, Bucana CD, Pathak S, Kruzel E, Herbst RS, Onn A, Roach JS, Onda M, Wang QC, Pastan I, Fidler IJ. Fan D, et al. Among authors: wang qc. Mol Cancer Ther. 2002 Jun;1(8):595-600. Mol Cancer Ther. 2002. PMID: 12479219

2

In vitro and in vivo cytotoxic activities of recombinant immunotoxin 8H9(Fv)-PE38 against breast cancer, osteosarcoma, and neuroblastoma.

Onda M, Wang QC, Guo HF, Cheung NK, Pastan I. Onda M, et al. Among authors: wang qc. Cancer Res. 2004 Feb 15;64(4):1419-24. doi: 10.1158/0008-5472.can-03-0570. Cancer Res. 2004. PMID: 14973056

3

An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes.

Onda M, Beers R, Xiang L, Nagata S, Wang QC, Pastan I. Onda M, et al. Among authors: wang qc. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11311-6. doi: 10.1073/pnas.0804851105. Epub 2008 Aug 4. Proc Natl Acad Sci U S A. 2008. PMID: 18678888 Free PMC article.

4

Humoral immune response to mesothelin in mesothelioma and ovarian cancer patients.

Ho M, Hassan R, Zhang J, Wang QC, Onda M, Bera T, Pastan I. Ho M, et al. Among authors: wang qc. Clin Cancer Res. 2005 May 15;11(10):3814-20. doi: 10.1158/1078-0432.CCR-04-2304. Clin Cancer Res. 2005. PMID: 15897581

5

Abrogation of head and neck squamous cell carcinoma growth by epidermal growth factor receptor ligand fused to pseudomonas exotoxin transforming growth factor alpha-PE38.

Thomas SM, Zeng Q, Epperly MW, Gooding WE, Pastan I, Wang QC, Greenberger J, Grandis JR. Thomas SM, et al. Among authors: wang qc. Clin Cancer Res. 2004 Oct 15;10(20):7079-87. doi: 10.1158/1078-0432.CCR-04-0587. Clin Cancer Res. 2004. PMID: 15501988

6

Antitumor activity of SS(dsFv)PE38 and SS1(dsFv)PE38, recombinant antimesothelin immunotoxins against human gynecologic cancers grown in organotypic culture in vitro.

Hassan R, Lerner MR, Benbrook D, Lightfoot SA, Brackett DJ, Wang QC, Pastan I. Hassan R, et al. Among authors: wang qc. Clin Cancer Res. 2002 Nov;8(11):3520-6. Clin Cancer Res. 2002. PMID: 12429643

7

Anti-HIV-1 immunotoxin 3B3(Fv)-PE38: enhanced potency against clinical isolates in human PBMCs and macrophages, and negligible hepatotoxicity in macaques.

Kennedy PE, Bera TK, Wang QC, Gallo M, Wagner W, Lewis MG, Berger EA, Pastan I. Kennedy PE, et al. Among authors: wang qc. J Leukoc Biol. 2006 Nov;80(5):1175-82. doi: 10.1189/jlb.0306139. Epub 2006 Aug 21. J Leukoc Biol. 2006. PMID: 16923920

8

Mesothelin is shed from tumor cells.

Ho M, Onda M, Wang QC, Hassan R, Pastan I, Lively MO. Ho M, et al. Among authors: wang qc. Cancer Epidemiol Biomarkers Prev. 2006 Sep;15(9):1751. doi: 10.1158/1055-9965.EPI-06-0479. Cancer Epidemiol Biomarkers Prev. 2006. PMID: 16985043 No abstract available.

9

Releasable PEGylation of mesothelin targeted immunotoxin SS1P achieves single dosage complete regression of a human carcinoma in mice.

Filpula D, Yang K, Basu A, Hassan R, Xiang L, Zhang Z, Wang M, Wang QC, Ho M, Beers R, Zhao H, Peng P, Zhou J, Li X, Petti G, Janjua A, Liu J, Wu D, Yu D, Zhang Z, Longley C, FitzGerald D, Kreitman RJ, Pastan I. Filpula D, et al. Among authors: wang qc, wang m. Bioconjug Chem. 2007 May-Jun;18(3):773-84. doi: 10.1021/bc060314x. Epub 2007 Mar 9. Bioconjug Chem. 2007. PMID: 17346030

10

Induction of caspase-dependent programmed cell death in B-cell chronic lymphocytic leukemia by anti-CD22 immunotoxins.

Decker T, Oelsner M, Kreitman RJ, Salvatore G, Wang QC, Pastan I, Peschel C, Licht T. Decker T, et al. Among authors: wang qc. Blood. 2004 Apr 1;103(7):2718-26. doi: 10.1182/blood-2003-04-1317. Epub 2003 Oct 2. Blood. 2004. PMID: 14525789 Free article.

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