Barnett-Norris J - Search Results

1

Activation of the cannabinoid CB1 receptor may involve a W6 48/F3 36 rotamer toggle switch.

Singh R, Hurst DP, Barnett-Norris J, Lynch DL, Reggio PH, Guarnieri F. Singh R, et al. Among authors: barnett norris j. J Pept Res. 2002 Dec;60(6):357-70. doi: 10.1034/j.1399-3011.2002.21065.x. J Pept Res. 2002. PMID: 12464114

2

Conformational memories and the endocannabinoid binding site at the cannabinoid CB1 receptor.

Barnett-Norris J, Hurst DP, Lynch DL, Guarnieri F, Makriyannis A, Reggio PH. Barnett-Norris J, et al. J Med Chem. 2002 Aug 15;45(17):3649-59. doi: 10.1021/jm0200761. J Med Chem. 2002. PMID: 12166938

3

N-(piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide (SR141716A) interaction with LYS 3.28(192) is crucial for its inverse agonism at the cannabinoid CB1 receptor.

Hurst DP, Lynch DL, Barnett-Norris J, Hyatt SM, Seltzman HH, Zhong M, Song ZH, Nie J, Lewis D, Reggio PH. Hurst DP, et al. Among authors: barnett norris j. Mol Pharmacol. 2002 Dec;62(6):1274-87. doi: 10.1124/mol.62.6.1274. Mol Pharmacol. 2002. PMID: 12435794

4

Structural mimicry in class A G protein-coupled receptor rotamer toggle switches: the importance of the F3.36(201)/W6.48(357) interaction in cannabinoid CB1 receptor activation.

McAllister SD, Hurst DP, Barnett-Norris J, Lynch D, Reggio PH, Abood ME. McAllister SD, et al. Among authors: barnett norris j. J Biol Chem. 2004 Nov 12;279(46):48024-37. doi: 10.1074/jbc.M406648200. Epub 2004 Aug 23. J Biol Chem. 2004. PMID: 15326174 Free article.

5

Lipids, lipid rafts and caveolae: their importance for GPCR signaling and their centrality to the endocannabinoid system.

Barnett-Norris J, Lynch D, Reggio PH. Barnett-Norris J, et al. Life Sci. 2005 Aug 19;77(14):1625-39. doi: 10.1016/j.lfs.2005.05.040. Life Sci. 2005. PMID: 15993425 Review.

6

Exploration of biologically relevant conformations of anandamide, 2-arachidonylglycerol, and their analogues using conformational memories.

Barnett-Norris J, Guarnieri F, Hurst DP, Reggio PH. Barnett-Norris J, et al. J Med Chem. 1998 Nov 19;41(24):4861-72. doi: 10.1021/jm9803471. J Med Chem. 1998. PMID: 9822555

7

The bioactive conformation of aminoalkylindoles at the cannabinoid CB1 and CB2 receptors: insights gained from (E)- and (Z)-naphthylidene indenes.

Reggio PH, Basu-Dutt S, Barnett-Norris J, Castro MT, Hurst DP, Seltzman HH, Roche MJ, Gilliam AF, Thomas BF, Stevenson LA, Pertwee RG, Abood ME. Reggio PH, et al. Among authors: barnett norris j. J Med Chem. 1998 Dec 17;41(26):5177-87. doi: 10.1021/jm9801197. J Med Chem. 1998. PMID: 9857088

8

A critical role for a tyrosine residue in the cannabinoid receptors for ligand recognition.

McAllister SD, Tao Q, Barnett-Norris J, Buehner K, Hurst DP, Guarnieri F, Reggio PH, Nowell Harmon KW, Cabral GA, Abood ME. McAllister SD, et al. Among authors: barnett norris j. Biochem Pharmacol. 2002 Jun 15;63(12):2121-36. doi: 10.1016/s0006-2952(02)01031-6. Biochem Pharmacol. 2002. PMID: 12110371

9

An aromatic microdomain at the cannabinoid CB(1) receptor constitutes an agonist/inverse agonist binding region.

McAllister SD, Rizvi G, Anavi-Goffer S, Hurst DP, Barnett-Norris J, Lynch DL, Reggio PH, Abood ME. McAllister SD, et al. Among authors: barnett norris j. J Med Chem. 2003 Nov 20;46(24):5139-52. doi: 10.1021/jm0302647. J Med Chem. 2003. PMID: 14613317

10

Cysteine 2.59(89) in the second transmembrane domain of human CB2 receptor is accessible within the ligand binding crevice: evidence for possible CB2 deviation from a rhodopsin template.

Zhang R, Hurst DP, Barnett-Norris J, Reggio PH, Song ZH. Zhang R, et al. Among authors: barnett norris j. Mol Pharmacol. 2005 Jul;68(1):69-83. doi: 10.1124/mol.104.007823. Epub 2005 Apr 19. Mol Pharmacol. 2005. PMID: 15840841

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