Takahashi R - Search Results

1

Proteasomal inhibition by misfolded mutant superoxide dismutase 1 induces selective motor neuron death in familial amyotrophic lateral sclerosis.

Urushitani M, Kurisu J, Tsukita K, Takahashi R. Urushitani M, et al. Among authors: takahashi r. J Neurochem. 2002 Dec;83(5):1030-42. doi: 10.1046/j.1471-4159.2002.01211.x. J Neurochem. 2002. PMID: 12437574 Free article.

2

Ubiquitin-protein ligase activity of X-linked inhibitor of apoptosis protein promotes proteasomal degradation of caspase-3 and enhances its anti-apoptotic effect in Fas-induced cell death.

Suzuki Y, Nakabayashi Y, Takahashi R. Suzuki Y, et al. Among authors: takahashi r. Proc Natl Acad Sci U S A. 2001 Jul 17;98(15):8662-7. doi: 10.1073/pnas.161506698. Epub 2001 Jul 10. Proc Natl Acad Sci U S A. 2001. PMID: 11447297 Free PMC article.

3

CHIP is associated with Parkin, a gene responsible for familial Parkinson's disease, and enhances its ubiquitin ligase activity.

Imai Y, Soda M, Hatakeyama S, Akagi T, Hashikawa T, Nakayama KI, Takahashi R. Imai Y, et al. Among authors: takahashi r. Mol Cell. 2002 Jul;10(1):55-67. doi: 10.1016/s1097-2765(02)00583-x. Mol Cell. 2002. PMID: 12150907 Free article.

4

A product of the human gene adjacent to parkin is a component of Lewy bodies and suppresses Pael receptor-induced cell death.

Imai Y, Soda M, Murakami T, Shoji M, Abe K, Takahashi R. Imai Y, et al. Among authors: takahashi r. J Biol Chem. 2003 Dec 19;278(51):51901-10. doi: 10.1074/jbc.M309655200. Epub 2003 Oct 7. J Biol Chem. 2003. PMID: 14532270 Free article.

5

The crucial role of caspase-9 in the disease progression of a transgenic ALS mouse model.

Inoue H, Tsukita K, Iwasato T, Suzuki Y, Tomioka M, Tateno M, Nagao M, Kawata A, Saido TC, Miura M, Misawa H, Itohara S, Takahashi R. Inoue H, et al. Among authors: takahashi r. EMBO J. 2003 Dec 15;22(24):6665-74. doi: 10.1093/emboj/cdg634. EMBO J. 2003. PMID: 14657037 Free PMC article.

6

siRNA-based inhibition specific for mutant SOD1 with single nucleotide alternation in familial ALS, compared with ribozyme and DNA enzyme.

Yokota T, Miyagishi M, Hino T, Matsumura R, Tasinato A, Urushitani M, Rao RV, Takahashi R, Bredesen DE, Taira K, Mizusawa H. Yokota T, et al. Among authors: takahashi r. Biochem Biophys Res Commun. 2004 Jan 30;314(1):283-91. doi: 10.1016/j.bbrc.2003.12.098. Biochem Biophys Res Commun. 2004. PMID: 14715277

7

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

Urushitani M, Kurisu J, Tateno M, Hatakeyama S, Nakayama K, Kato S, Takahashi R. Urushitani M, et al. Among authors: takahashi r. J Neurochem. 2004 Jul;90(1):231-44. doi: 10.1111/j.1471-4159.2004.02486.x. J Neurochem. 2004. PMID: 15198682 Free article.

8

Calcium-permeable AMPA receptors promote misfolding of mutant SOD1 protein and development of amyotrophic lateral sclerosis in a transgenic mouse model.

Tateno M, Sadakata H, Tanaka M, Itohara S, Shin RM, Miura M, Masuda M, Aosaki T, Urushitani M, Misawa H, Takahashi R. Tateno M, et al. Among authors: takahashi r. Hum Mol Genet. 2004 Oct 1;13(19):2183-96. doi: 10.1093/hmg/ddh246. Epub 2004 Aug 4. Hum Mol Genet. 2004. PMID: 15294873

9

U-box protein carboxyl terminus of Hsc70-interacting protein (CHIP) mediates poly-ubiquitylation preferentially on four-repeat Tau and is involved in neurodegeneration of tauopathy.

Hatakeyama S, Matsumoto M, Kamura T, Murayama M, Chui DH, Planel E, Takahashi R, Nakayama KI, Takashima A. Hatakeyama S, et al. Among authors: takahashi r. J Neurochem. 2004 Oct;91(2):299-307. doi: 10.1111/j.1471-4159.2004.02713.x. J Neurochem. 2004. PMID: 15447663 Free article.

10

Unsaturated fatty acids induce cytotoxic aggregate formation of amyotrophic lateral sclerosis-linked superoxide dismutase 1 mutants.

Kim YJ, Nakatomi R, Akagi T, Hashikawa T, Takahashi R. Kim YJ, et al. Among authors: takahashi r. J Biol Chem. 2005 Jun 3;280(22):21515-21. doi: 10.1074/jbc.M502230200. Epub 2005 Mar 29. J Biol Chem. 2005. PMID: 15799963 Free article.

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