Getzoff ED - Search Results

1

Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency.

Rosenfeld RJ, Garcin ED, Panda K, Andersson G, Aberg A, Wallace AV, Morris GM, Olson AJ, Stuehr DJ, Tainer JA, Getzoff ED. Rosenfeld RJ, et al. Among authors: getzoff ed. Biochemistry. 2002 Nov 26;41(47):13915-25. doi: 10.1021/bi026313j. Biochemistry. 2002. PMID: 12437348

2

Structural basis for endothelial nitric oxide synthase binding to calmodulin.

Aoyagi M, Arvai AS, Tainer JA, Getzoff ED. Aoyagi M, et al. Among authors: getzoff ed. EMBO J. 2003 Feb 17;22(4):766-75. doi: 10.1093/emboj/cdg078. EMBO J. 2003. PMID: 12574113 Free PMC article.

3

Structural basis for isozyme-specific regulation of electron transfer in nitric-oxide synthase.

Garcin ED, Bruns CM, Lloyd SJ, Hosfield DJ, Tiso M, Gachhui R, Stuehr DJ, Tainer JA, Getzoff ED. Garcin ED, et al. Among authors: getzoff ed. J Biol Chem. 2004 Sep 3;279(36):37918-27. doi: 10.1074/jbc.M406204200. Epub 2004 Jun 17. J Biol Chem. 2004. PMID: 15208315 Free article.

4

Nickel superoxide dismutase structure and mechanism.

Barondeau DP, Kassmann CJ, Bruns CK, Tainer JA, Getzoff ED. Barondeau DP, et al. Among authors: getzoff ed. Biochemistry. 2004 Jun 29;43(25):8038-47. doi: 10.1021/bi0496081. Biochemistry. 2004. PMID: 15209499

5

Understanding GFP chromophore biosynthesis: controlling backbone cyclization and modifying post-translational chemistry.

Barondeau DP, Kassmann CJ, Tainer JA, Getzoff ED. Barondeau DP, et al. Among authors: getzoff ed. Biochemistry. 2005 Feb 15;44(6):1960-70. doi: 10.1021/bi0479205. Biochemistry. 2005. PMID: 15697221

6

Crystallographic structures of Discosoma red fluorescent protein with immature and mature chromophores: linking peptide bond trans-cis isomerization and acylimine formation in chromophore maturation.

Tubbs JL, Tainer JA, Getzoff ED. Tubbs JL, et al. Among authors: getzoff ed. Biochemistry. 2005 Jul 26;44(29):9833-40. doi: 10.1021/bi0472907. Biochemistry. 2005. PMID: 16026155

7

Anchored plasticity opens doors for selective inhibitor design in nitric oxide synthase.

Garcin ED, Arvai AS, Rosenfeld RJ, Kroeger MD, Crane BR, Andersson G, Andrews G, Hamley PJ, Mallinder PR, Nicholls DJ, St-Gallay SA, Tinker AC, Gensmantel NP, Mete A, Cheshire DR, Connolly S, Stuehr DJ, Aberg A, Wallace AV, Tainer JA, Getzoff ED. Garcin ED, et al. Among authors: getzoff ed. Nat Chem Biol. 2008 Nov;4(11):700-7. doi: 10.1038/nchembio.115. Epub 2008 Oct 12. Nat Chem Biol. 2008. PMID: 18849972 Free PMC article.

8

The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.

Crane BR, Arvai AS, Gachhui R, Wu C, Ghosh DK, Getzoff ED, Stuehr DJ, Tainer JA. Crane BR, et al. Among authors: getzoff ed. Science. 1997 Oct 17;278(5337):425-31. doi: 10.1126/science.278.5337.425. Science. 1997. PMID: 9334294

9

Structure of nitric oxide synthase oxygenase dimer with pterin and substrate.

Crane BR, Arvai AS, Ghosh DK, Wu C, Getzoff ED, Stuehr DJ, Tainer JA. Crane BR, et al. Among authors: getzoff ed. Science. 1998 Mar 27;279(5359):2121-6. doi: 10.1126/science.279.5359.2121. Science. 1998. PMID: 9516116

10

N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization.

Crane BR, Rosenfeld RJ, Arvai AS, Ghosh DK, Ghosh S, Tainer JA, Stuehr DJ, Getzoff ED. Crane BR, et al. Among authors: getzoff ed. EMBO J. 1999 Nov 15;18(22):6271-81. doi: 10.1093/emboj/18.22.6271. EMBO J. 1999. PMID: 10562539 Free PMC article.

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