Loxham SJ - Search Results

1

The temporal relationship between glycogen phosphorylase and activation of the pyruvate dehydrogenase complex during adrenaline infusion in resting canine skeletal muscle.

Roberts PA, Loxham SJ, Poucher SM, Constantin-Teodosiu D, Greenhaff PL. Roberts PA, et al. Among authors: loxham sj. J Physiol. 2002 Nov 15;545(1):297-304. doi: 10.1113/jphysiol.2002.021055. J Physiol. 2002. PMID: 12433969 Free PMC article.

2

The acetyl group deficit at the onset of contraction in ischaemic canine skeletal muscle.

Roberts PA, Loxham SJ, Poucher SM, Constantin-Teodosiu D, Greenhaff PL. Roberts PA, et al. Among authors: loxham sj. J Physiol. 2002 Oct 15;544(2):591-602. doi: 10.1113/jphysiol.2002.021097. J Physiol. 2002. PMID: 12381829 Free PMC article.

3

Bicarbonate-induced alkalosis augments cellular acetyl group availability and isometric force during the rest-to-work transition in canine skeletal muscle.

Roberts PA, Loxham SJ, Poucher SM, Constantin-Teodosiu D, Greenhaff PL. Roberts PA, et al. Among authors: loxham sj. Exp Physiol. 2002 Jul;87(4):489-98. doi: 10.1111/j.1469-445x.2002.tb00062.x. Exp Physiol. 2002. PMID: 12392113

4

Acetyl-CoA provision and the acetyl group deficit at the onset of contraction in ischemic canine skeletal muscle.

Roberts PA, Loxham SJ, Poucher SM, Constantin-Teodosiu D, Greenhaff PL. Roberts PA, et al. Among authors: loxham sj. Am J Physiol Endocrinol Metab. 2005 Feb;288(2):E327-34. doi: 10.1152/ajpendo.00441.2003. Epub 2004 Sep 28. Am J Physiol Endocrinol Metab. 2005. PMID: 15454400 Free article.

5

Sensitivity of glycogen phosphorylase isoforms to indole site inhibitors is markedly dependent on the activation state of the enzyme.

Freeman S, Bartlett JB, Convey G, Hardern I, Teague JL, Loxham SJ, Allen JM, Poucher SM, Charles AD. Freeman S, et al. Among authors: loxham sj. Br J Pharmacol. 2006 Nov;149(6):775-85. doi: 10.1038/sj.bjp.0706925. Epub 2006 Oct 3. Br J Pharmacol. 2006. PMID: 17016495 Free PMC article.

6

Glucagon challenge in the rat: a robust method for the in vivo assessment of Glycogen phosphorlyase inhibitor efficacy.

Loxham SJ, Teague J, Poucher SM, De Schoolmeester J, Turnbull AV, Carey F. Loxham SJ, et al. J Pharmacol Toxicol Methods. 2007 Jan-Feb;55(1):71-7. doi: 10.1016/j.vascn.2006.03.005. Epub 2006 Mar 27. J Pharmacol Toxicol Methods. 2007. PMID: 16713718

7

An assessment of the in vivo efficacy of the glycogen phosphorylase inhibitor GPi688 in rat models of hyperglycaemia.

Poucher SM, Freeman S, Loxham SJ, Convey G, Bartlett JB, De Schoolmeester J, Teague J, Walker M, Turnbull AV, Charles AD, Carey F, Berg S. Poucher SM, et al. Among authors: loxham sj. Br J Pharmacol. 2007 Dec;152(8):1239-47. doi: 10.1038/sj.bjp.0707502. Epub 2007 Oct 15. Br J Pharmacol. 2007. PMID: 17934512 Free PMC article.

8

The intravenous glucose tolerance test in cannulated Wistar rats: a robust method for the in vivo assessment of glucose-stimulated insulin secretion.

Frangioudakis G, Gyte AC, Loxham SJ, Poucher SM. Frangioudakis G, et al. Among authors: loxham sj. J Pharmacol Toxicol Methods. 2008 Mar-Apr;57(2):106-13. doi: 10.1016/j.vascn.2007.12.002. Epub 2008 Jan 10. J Pharmacol Toxicol Methods. 2008. PMID: 18280184

9

Reversibility of hyperglycaemia and islet abnormalities in the high fat-fed female ZDF rat model of type 2 diabetes.

Teague J, Gyte A, Peel JE, Young KC, Loxham SJ, Mayers RM, Poucher SM. Teague J, et al. Among authors: loxham sj. J Pharmacol Toxicol Methods. 2011 Jan-Feb;63(1):15-23. doi: 10.1016/j.vascn.2010.04.001. Epub 2010 Apr 14. J Pharmacol Toxicol Methods. 2011. PMID: 20398780

10

Selective antagonism of the NPY Y5 receptor does not have a major effect on feeding in rats.

Turnbull AV, Ellershaw L, Masters DJ, Birtles S, Boyer S, Carroll D, Clarkson P, Loxham SJ, McAulay P, Teague JL, Foote KM, Pease JE, Block MH. Turnbull AV, et al. Among authors: loxham sj. Diabetes. 2002 Aug;51(8):2441-9. doi: 10.2337/diabetes.51.8.2441. Diabetes. 2002. PMID: 12145156

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