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Phase I trial of the proteasome inhibitor PS-341 in patients with refractory hematologic malignancies.
Orlowski RZ, Stinchcombe TE, Mitchell BS, Shea TC, Baldwin AS, Stahl S, Adams J, Esseltine DL, Elliott PJ, Pien CS, Guerciolini R, Anderson JK, Depcik-Smith ND, Bhagat R, Lehman MJ, Novick SC, O'Connor OA, Soignet SL. Orlowski RZ, et al. Among authors: baldwin as. J Clin Oncol. 2002 Nov 15;20(22):4420-7. doi: 10.1200/JCO.2002.01.133. J Clin Oncol. 2002. PMID: 12431963 Clinical Trial.
NF-kappaB as a therapeutic target in cancer.
Orlowski RZ, Baldwin AS Jr. Orlowski RZ, et al. Among authors: baldwin as jr. Trends Mol Med. 2002 Aug;8(8):385-9. doi: 10.1016/s1471-4914(02)02375-4. Trends Mol Med. 2002. PMID: 12127724 Review.
Proteasome inhibition ablates activation of NF-kappa B in myocardial reperfusion and reduces reperfusion injury.
Pye J, Ardeshirpour F, McCain A, Bellinger DA, Merricks E, Adams J, Elliott PJ, Pien C, Fischer TH, Baldwin AS Jr, Nichols TC. Pye J, et al. Among authors: baldwin as jr. Am J Physiol Heart Circ Physiol. 2003 Mar;284(3):H919-26. doi: 10.1152/ajpheart.00851.2002. Epub 2002 Nov 7. Am J Physiol Heart Circ Physiol. 2003. PMID: 12424098 Free article.
B cells from patients with chronic GVHD are activated and primed for survival via BAFF-mediated pathways.
Allen JL, Fore MS, Wooten J, Roehrs PA, Bhuiya NS, Hoffert T, Sharf A, Deal AM, Armistead P, Coghill J, Gabriel DA, Irons R, Essenmacher A, Shea TC, Richards K, Cutler C, Ritz J, Serody J, Baldwin AS, Sarantopoulos S. Allen JL, et al. Among authors: baldwin as. Blood. 2012 Sep 20;120(12):2529-36. doi: 10.1182/blood-2012-06-438911. Epub 2012 Aug 14. Blood. 2012. PMID: 22896003 Free PMC article.
Proteasome inhibition promotes regression of left ventricular hypertrophy.
Stansfield WE, Tang RH, Moss NC, Baldwin AS, Willis MS, Selzman CH. Stansfield WE, et al. Among authors: baldwin as. Am J Physiol Heart Circ Physiol. 2008 Feb;294(2):H645-50. doi: 10.1152/ajpheart.00196.2007. Epub 2007 Nov 21. Am J Physiol Heart Circ Physiol. 2008. PMID: 18032525 Free article.
308 results