Prestwich GD - Search Results

1

Synthesis of chiral (alpha,alpha-difluoroalkyl)phosphonate analogues of (lyso)phosphatidic acid via hydrolytic kinetic resolution.

Xu Y, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Org Lett. 2002 Nov 14;4(23):4021-4. doi: 10.1021/ol026684s. Org Lett. 2002. PMID: 12423076

2

New metabolically stabilized analogues of lysophosphatidic acid: agonists, antagonists and enzyme inhibitors.

Prestwich GD, Xu Y, Qian L, Gajewiak J, Jiang G. Prestwich GD, et al. Biochem Soc Trans. 2005 Dec;33(Pt 6):1357-61. doi: 10.1042/BST0331357. Biochem Soc Trans. 2005. PMID: 16246118 Review.

3

Concise synthesis of acyl migration-blocked 1,1-difluorinated analogues of lysophosphatidic acid.

Xu Y, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. J Org Chem. 2002 Oct 4;67(20):7158-61. doi: 10.1021/jo0203037. J Org Chem. 2002. PMID: 12354017

4

Synthesis of alpha-fluorinated phosphonates from alpha-fluorovinylphosphonates: a new route to analogues of lysophosphatidic acid.

Xu Y, Qian L, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Org Lett. 2003 Jun 26;5(13):2267-70. doi: 10.1021/ol034597+. Org Lett. 2003. PMID: 12816425

5

Synthesis of monofluorinated analogues of lysophosphatidic acid.

Xu Y, Qian L, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. J Org Chem. 2003 Jun 27;68(13):5320-30. doi: 10.1021/jo020729l. J Org Chem. 2003. PMID: 12816494

6

Synthesis of migration-resistant hydroxyethoxy analogues of lysophosphatidic acid.

Qian L, Xu Y, Arai H, Aoki J, McIntyre TM, Prestwich GD. Qian L, et al. Among authors: prestwich gd. Org Lett. 2003 Nov 27;5(24):4685-8. doi: 10.1021/ol0358758. Org Lett. 2003. PMID: 14627415

7

Activation of mTOR signaling by novel fluoromethylene phosphonate analogues of phosphatidic acid.

Xu Y, Fang Y, Chen J, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Bioorg Med Chem Lett. 2004 Mar 22;14(6):1461-4. doi: 10.1016/j.bmcl.2004.01.020. Bioorg Med Chem Lett. 2004. PMID: 15006382

8

Alkyl lysophosphatidic acid and fluoromethylene phosphonate analogs as metabolically-stabilized agonists for LPA receptors.

Xu Y, Tanaka M, Arai H, Aoki J, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. Bioorg Med Chem Lett. 2004 Nov 1;14(21):5323-8. doi: 10.1016/j.bmcl.2004.08.019. Bioorg Med Chem Lett. 2004. PMID: 15454220

9

Structure-activity relationships of fluorinated lysophosphatidic acid analogues.

Xu Y, Aoki J, Shimizu K, Umezu-Goto M, Hama K, Takanezawa Y, Yu S, Mills GB, Arai H, Qian L, Prestwich GD. Xu Y, et al. Among authors: prestwich gd. J Med Chem. 2005 May 5;48(9):3319-27. doi: 10.1021/jm049186t. J Med Chem. 2005. PMID: 15857137

10

Concise synthesis of ether analogues of lysobisphosphatidic acid.

Jiang G, Xu Y, Falguières T, Gruenberg J, Prestwich GD. Jiang G, et al. Among authors: prestwich gd. Org Lett. 2005 Sep 1;7(18):3837-40. doi: 10.1021/ol051194w. Org Lett. 2005. PMID: 16119911 Free PMC article.

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