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Caspase activation and neuroprotection in caspase-3- deficient mice after in vivo cerebral ischemia and in vitro oxygen glucose deprivation.
Le DA, Wu Y, Huang Z, Matsushita K, Plesnila N, Augustinack JC, Hyman BT, Yuan J, Kuida K, Flavell RA, Moskowitz MA. Le DA, et al. Among authors: flavell ra. Proc Natl Acad Sci U S A. 2002 Nov 12;99(23):15188-93. doi: 10.1073/pnas.232473399. Epub 2002 Nov 1. Proc Natl Acad Sci U S A. 2002. PMID: 12415117 Free PMC article.
Sensing DNA as danger: The discovery of cGAS.
Flavell RA, Sefik E. Flavell RA, et al. Immunity. 2024 Oct 8;57(10):2251-2254. doi: 10.1016/j.immuni.2024.09.009. Epub 2024 Sep 19. Immunity. 2024. PMID: 39303723
The human CD47 checkpoint is targeted by an immunosuppressive Aedes aegypti salivary factor to enhance arboviral skin infectivity.
Marin-Lopez A, Huck JD, Esterly AT, Azcutia V, Rosen C, Garcia-Milian R, Sefik E, Vidal-Pedrola G, Raduwan H, Chen TY, Arora G, Halene S, Shaw AC, Palm NW, Flavell RA, Parkos CA, Thangamani S, Ring AM, Fikrig E. Marin-Lopez A, et al. Among authors: flavell ra. Sci Immunol. 2024 Aug 9;9(98):eadk9872. doi: 10.1126/sciimmunol.adk9872. Epub 2024 Aug 9. Sci Immunol. 2024. PMID: 39121194
UBXN3B is crucial for B lymphopoiesis.
Geng T, Yang D, Lin T, Harrison AG, Wang B, Cao Z, Torrance B, Fan Z, Wang K, Wang Y, Yang L, Haynes L, Cheng G, Vella AT, Flavell RA, Pereira JP, Fikrig E, Wang P. Geng T, et al. Among authors: flavell ra. EBioMedicine. 2024 Aug;106:105248. doi: 10.1016/j.ebiom.2024.105248. Epub 2024 Jul 16. EBioMedicine. 2024. PMID: 39018756 Free PMC article.
A metabolic switch orchestrated by IL-18 and the cyclic dinucleotide cGAMP programs intestinal tolerance.
Mertens RT, Misra A, Xiao P, Baek S, Rone JM, Mangani D, Sivanathan KN, Arojojoye AS, Awuah SG, Lee I, Shi GP, Petrova B, Brook JR, Anderson AC, Flavell RA, Kanarek N, Hemberg M, Nowarski R. Mertens RT, et al. Among authors: flavell ra. Immunity. 2024 Sep 10;57(9):2077-2094.e12. doi: 10.1016/j.immuni.2024.06.001. Epub 2024 Jun 20. Immunity. 2024. PMID: 38906145
1,217 results