Schiedner G - Search Results

1

Therapeutic factor VIII levels and negligible toxicity in mouse and dog models of hemophilia A following gene therapy with high-capacity adenoviral vectors.

Chuah MK, Schiedner G, Thorrez L, Brown B, Johnston M, Gillijns V, Hertel S, Van Rooijen N, Lillicrap D, Collen D, VandenDriessche T, Kochanek S. Chuah MK, et al. Among authors: schiedner g. Blood. 2003 Mar 1;101(5):1734-43. doi: 10.1182/blood-2002-03-0823. Epub 2002 Oct 24. Blood. 2003. PMID: 12406898 Free article.

2

Variables affecting in vivo performance of high-capacity adenovirus vectors.

Schiedner G, Hertel S, Johnston M, Biermann V, Dries V, Kochanek S. Schiedner G, et al. J Virol. 2002 Feb;76(4):1600-9. doi: 10.1128/jvi.76.4.1600-1609.2002. J Virol. 2002. PMID: 11799154 Free PMC article.

3

Selective depletion or blockade of Kupffer cells leads to enhanced and prolonged hepatic transgene expression using high-capacity adenoviral vectors.

Schiedner G, Hertel S, Johnston M, Dries V, van Rooijen N, Kochanek S. Schiedner G, et al. Mol Ther. 2003 Jan;7(1):35-43. doi: 10.1016/s1525-0016(02)00017-5. Mol Ther. 2003. PMID: 12573616 Free article.

4

Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity, adenovirus vectors: toward realistic long-term neurological gene therapy for chronic diseases.

Thomas CE, Schiedner G, Kochanek S, Castro MG, Löwenstein PR. Thomas CE, et al. Among authors: schiedner g. Proc Natl Acad Sci U S A. 2000 Jun 20;97(13):7482-7. doi: 10.1073/pnas.120474397. Proc Natl Acad Sci U S A. 2000. PMID: 10840055 Free PMC article.

5

Preexisting antiadenoviral immunity is not a barrier to efficient and stable transduction of the brain, mediated by novel high-capacity adenovirus vectors.

Thomas CE, Schiedner G, Kochanek S, Castro MG, Lowenstein PR. Thomas CE, et al. Among authors: schiedner g. Hum Gene Ther. 2001 May 1;12(7):839-46. doi: 10.1089/104303401750148829. Hum Gene Ther. 2001. PMID: 11339900

6

High-capacity 'gutless' adenoviral vectors.

Kochanek S, Schiedner G, Volpers C. Kochanek S, et al. Among authors: schiedner g. Curr Opin Mol Ther. 2001 Oct;3(5):454-63. Curr Opin Mol Ther. 2001. PMID: 11699889 Review.

7

Sustained muscle expression of dystrophin from a high-capacity adenoviral vector with systemic gene transfer of T cell costimulatory blockade.

Jiang Z, Schiedner G, van Rooijen N, Liu CC, Kochanek S, Clemens PR. Jiang Z, et al. Among authors: schiedner g. Mol Ther. 2004 Oct;10(4):688-96. doi: 10.1016/j.ymthe.2004.07.020. Mol Ther. 2004. PMID: 15451453 Free article.

8

A DNA-based method to assay total and infectious particle contents and helper virus contamination in high-capacity adenoviral vector preparations.

Kreppel F, Biermann V, Kochanek S, Schiedner G. Kreppel F, et al. Among authors: schiedner g. Hum Gene Ther. 2002 Jul 1;13(10):1151-6. doi: 10.1089/104303402320138934. Hum Gene Ther. 2002. PMID: 12133268

9

A hemodynamic response to intravenous adenovirus vector particles is caused by systemic Kupffer cell-mediated activation of endothelial cells.

Schiedner G, Bloch W, Hertel S, Johnston M, Molojavyi A, Dries V, Varga G, Van Rooijen N, Kochanek S. Schiedner G, et al. Hum Gene Ther. 2003 Nov 20;14(17):1631-41. doi: 10.1089/104303403322542275. Hum Gene Ther. 2003. PMID: 14633405

10

Efficient transformation of primary human amniocytes by E1 functions of Ad5: generation of new cell lines for adenoviral vector production.

Schiedner G, Hertel S, Kochanek S. Schiedner G, et al. Hum Gene Ther. 2000 Oct 10;11(15):2105-16. doi: 10.1089/104303400750001417. Hum Gene Ther. 2000. PMID: 11044912

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