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Hes1 suppresses acute myeloid leukemia development through FLT3 repression.
Kato T, Sakata-Yanagimoto M, Nishikii H, Ueno M, Miyake Y, Yokoyama Y, Asabe Y, Kamada Y, Muto H, Obara N, Suzukawa K, Hasegawa Y, Kitabayashi I, Uchida K, Hirao A, Yagita H, Kageyama R, Chiba S. Kato T, et al. Among authors: kageyama r. Leukemia. 2015 Mar;29(3):576-85. doi: 10.1038/leu.2014.281. Epub 2014 Sep 19. Leukemia. 2015. PMID: 25234168
Developing HSCs become Notch independent by the end of maturation in the AGM region.
Souilhol C, Lendinez JG, Rybtsov S, Murphy F, Wilson H, Hills D, Batsivari A, Binagui-Casas A, McGarvey AC, MacDonald HR, Kageyama R, Siebel C, Zhao S, Medvinsky A. Souilhol C, et al. Among authors: kageyama r. Blood. 2016 Sep 22;128(12):1567-77. doi: 10.1182/blood-2016-03-708164. Epub 2016 Jul 15. Blood. 2016. PMID: 27421959 Free PMC article.
Notch-Hes1 pathway is required for the development of IL-17-producing γδ T cells.
Shibata K, Yamada H, Sato T, Dejima T, Nakamura M, Ikawa T, Hara H, Yamasaki S, Kageyama R, Iwakura Y, Kawamoto H, Toh H, Yoshikai Y. Shibata K, et al. Among authors: kageyama r. Blood. 2011 Jul 21;118(3):586-93. doi: 10.1182/blood-2011-02-334995. Epub 2011 May 23. Blood. 2011. PMID: 21606479 Free article.
Therapeutic targeting of HES1 transcriptional programs in T-ALL.
Schnell SA, Ambesi-Impiombato A, Sanchez-Martin M, Belver L, Xu L, Qin Y, Kageyama R, Ferrando AA. Schnell SA, et al. Among authors: kageyama r. Blood. 2015 Apr 30;125(18):2806-14. doi: 10.1182/blood-2014-10-608448. Epub 2015 Mar 17. Blood. 2015. PMID: 25784680 Free PMC article.
379 results