Muller GW - Search Results

1

Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects.

Dredge K, Marriott JB, Macdonald CD, Man HW, Chen R, Muller GW, Stirling D, Dalgleish AG. Dredge K, et al. Among authors: muller gw. Br J Cancer. 2002 Nov 4;87(10):1166-72. doi: 10.1038/sj.bjc.6600607. Br J Cancer. 2002. PMID: 12402158 Free PMC article.

2

Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro.

Dredge K, Horsfall R, Robinson SP, Zhang LH, Lu L, Tang Y, Shirley MA, Muller G, Schafer P, Stirling D, Dalgleish AG, Bartlett JB. Dredge K, et al. Microvasc Res. 2005 Jan;69(1-2):56-63. doi: 10.1016/j.mvr.2005.01.002. Microvasc Res. 2005. PMID: 15797261

3

The anti-cancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells.

Galustian C, Meyer B, Labarthe MC, Dredge K, Klaschka D, Henry J, Todryk S, Chen R, Muller G, Stirling D, Schafer P, Bartlett JB, Dalgleish AG. Galustian C, et al. Cancer Immunol Immunother. 2009 Jul;58(7):1033-45. doi: 10.1007/s00262-008-0620-4. Epub 2008 Nov 14. Cancer Immunol Immunother. 2009. PMID: 19009291 Free PMC article.

4

A novel subclass of thalidomide analogue with anti-solid tumor activity in which caspase-dependent apoptosis is associated with altered expression of bcl-2 family proteins.

Marriott JB, Clarke IA, Czajka A, Dredge K, Childs K, Man HW, Schafer P, Govinda S, Muller GW, Stirling DI, Dalgleish AG. Marriott JB, et al. Among authors: muller gw. Cancer Res. 2003 Feb 1;63(3):593-9. Cancer Res. 2003. PMID: 12566301

5

CC-3052: a water-soluble analog of thalidomide and potent inhibitor of activation-induced TNF-alpha production.

Marriott JB, Westby M, Cookson S, Guckian M, Goodbourn S, Muller G, Shire MG, Stirling D, Dalgleish AG. Marriott JB, et al. J Immunol. 1998 Oct 15;161(8):4236-43. J Immunol. 1998. PMID: 9780198

6

Thalidomide as an emerging immunotherapeutic agent.

Marriott JB, Muller G, Dalgleish AG. Marriott JB, et al. Immunol Today. 1999 Dec;20(12):538-40. doi: 10.1016/s0167-5699(99)01531-5. Immunol Today. 1999. PMID: 10562702 Review. No abstract available.

7

Immunotherapeutic and antitumour potential of thalidomide analogues.

Marriott JB, Muller G, Stirling D, Dalgleish AG. Marriott JB, et al. Expert Opin Biol Ther. 2001 Jul;1(4):675-82. doi: 10.1517/14712598.1.4.675. Expert Opin Biol Ther. 2001. PMID: 11727503 Review.

8

Thalidomide and its analogues have distinct and opposing effects on TNF-alpha and TNFR2 during co-stimulation of both CD4(+) and CD8(+) T cells.

Marriott JB, Clarke IA, Dredge K, Muller G, Stirling D, Dalgleish AG. Marriott JB, et al. Clin Exp Immunol. 2002 Oct;130(1):75-84. doi: 10.1046/j.1365-2249.2002.01954.x. Clin Exp Immunol. 2002. PMID: 12296856 Free PMC article. Clinical Trial.

9

Phase I study to determine the safety, tolerability and immunostimulatory activity of thalidomide analogue CC-5013 in patients with metastatic malignant melanoma and other advanced cancers.

Bartlett JB, Michael A, Clarke IA, Dredge K, Nicholson S, Kristeleit H, Polychronis A, Pandha H, Muller GW, Stirling DI, Zeldis J, Dalgleish AG. Bartlett JB, et al. Among authors: muller gw. Br J Cancer. 2004 Mar 8;90(5):955-61. doi: 10.1038/sj.bjc.6601579. Br J Cancer. 2004. PMID: 14997189 Free PMC article. Clinical Trial.

10

Protective antitumor immunity induced by a costimulatory thalidomide analog in conjunction with whole tumor cell vaccination is mediated by increased Th1-type immunity.

Dredge K, Marriott JB, Todryk SM, Muller GW, Chen R, Stirling DI, Dalgleish AG. Dredge K, et al. Among authors: muller gw. J Immunol. 2002 May 15;168(10):4914-9. doi: 10.4049/jimmunol.168.10.4914. J Immunol. 2002. PMID: 11994441

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