Tachedjian G - Search Results

1

Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules.

Sluis-Cremer N, Tachedjian G. Sluis-Cremer N, et al. Among authors: tachedjian g. Eur J Biochem. 2002 Nov;269(21):5103-11. doi: 10.1046/j.1432-1033.2002.03216.x. Eur J Biochem. 2002. PMID: 12392542 Free article. Review.

2

Efavirenz enhances the proteolytic processing of an HIV-1 pol polyprotein precursor and reverse transcriptase homodimer formation.

Tachedjian G, Moore KL, Goff SP, Sluis-Cremer N. Tachedjian G, et al. FEBS Lett. 2005 Jan 17;579(2):379-84. doi: 10.1016/j.febslet.2004.11.099. FEBS Lett. 2005. PMID: 15642347 Free article.

3

Relationship between enzyme activity and dimeric structure of recombinant HIV-1 reverse transcriptase.

Tachedjian G, Radzio J, Sluis-Cremer N. Tachedjian G, et al. Proteins. 2005 Jul 1;60(1):5-13. doi: 10.1002/prot.20480. Proteins. 2005. PMID: 15852304

4

Dimerization of human immunodeficiency virus type 1 reverse transcriptase as an antiviral target.

Srivastava S, Sluis-Cremer N, Tachedjian G. Srivastava S, et al. Among authors: tachedjian g. Curr Pharm Des. 2006;12(15):1879-94. doi: 10.2174/138161206776873590. Curr Pharm Des. 2006. PMID: 16724954 Review.

5

Potent nonnucleoside reverse transcriptase inhibitors target HIV-1 Gag-Pol.

Figueiredo A, Moore KL, Mak J, Sluis-Cremer N, de Bethune MP, Tachedjian G. Figueiredo A, et al. Among authors: tachedjian g. PLoS Pathog. 2006 Nov;2(11):e119. doi: 10.1371/journal.ppat.0020119. PLoS Pathog. 2006. PMID: 17096588 Free PMC article.

6

Characterization of novel non-nucleoside reverse transcriptase (RT) inhibitor resistance mutations at residues 132 and 135 in the 51 kDa subunit of HIV-1 RT.

Nissley DV, Radzio J, Ambrose Z, Sheen CW, Hamamouch N, Moore KL, Tachedjian G, Sluis-Cremer N. Nissley DV, et al. Among authors: tachedjian g. Biochem J. 2007 May 15;404(1):151-7. doi: 10.1042/BJ20061814. Biochem J. 2007. PMID: 17286555 Free PMC article.

7

N348I in the connection domain of HIV-1 reverse transcriptase confers zidovudine and nevirapine resistance.

Yap SH, Sheen CW, Fahey J, Zanin M, Tyssen D, Lima VD, Wynhoven B, Kuiper M, Sluis-Cremer N, Harrigan PR, Tachedjian G. Yap SH, et al. Among authors: tachedjian g. PLoS Med. 2007 Dec;4(12):e335. doi: 10.1371/journal.pmed.0040335. PLoS Med. 2007. PMID: 18052601 Free PMC article.

8

Impact of residues in the nonnucleoside reverse transcriptase inhibitor binding pocket on HIV-1 reverse transcriptase heterodimer stability.

Figueiredo A, Zelina S, Sluis-Cremer N, Tachedjian G. Figueiredo A, et al. Among authors: tachedjian g. Curr HIV Res. 2008 Mar;6(2):130-7. doi: 10.2174/157016208783885065. Curr HIV Res. 2008. PMID: 18336260

9

Mechanisms of inhibition of HIV replication by non-nucleoside reverse transcriptase inhibitors.

Sluis-Cremer N, Tachedjian G. Sluis-Cremer N, et al. Among authors: tachedjian g. Virus Res. 2008 Jun;134(1-2):147-56. doi: 10.1016/j.virusres.2008.01.002. Epub 2008 Mar 26. Virus Res. 2008. PMID: 18372072 Free PMC article. Review.

10

The human immunodeficiency virus type 1 nonnucleoside reverse transcriptase inhibitor resistance mutation I132M confers hypersensitivity to nucleoside analogs.

Ambrose Z, Herman BD, Sheen CW, Zelina S, Moore KL, Tachedjian G, Nissley DV, Sluis-Cremer N. Ambrose Z, et al. Among authors: tachedjian g. J Virol. 2009 Apr;83(8):3826-33. doi: 10.1128/JVI.01968-08. Epub 2009 Feb 4. J Virol. 2009. PMID: 19193782 Free PMC article.

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