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Transforming growth factor-beta (TGF-beta) binding to the extracellular domain of the type II TGF-beta receptor: receptor capture on a biosensor surface using a new coiled-coil capture system demonstrates that avidity contributes significantly to high affinity binding.
De Crescenzo G, Pham PL, Durocher Y, O'Connor-McCourt MD. De Crescenzo G, et al. J Mol Biol. 2003 May 16;328(5):1173-83. doi: 10.1016/s0022-2836(03)00360-7. J Mol Biol. 2003. PMID: 12729750
Real-time monitoring of the interactions of transforming growth factor-beta (TGF-beta ) isoforms with latency-associated protein and the ectodomains of the TGF-beta type II and III receptors reveals different kinetic models and stoichiometries of binding.
De Crescenzo G, Grothe S, Zwaagstra J, Tsang M, O'Connor-McCourt MD. De Crescenzo G, et al. J Biol Chem. 2001 Aug 10;276(32):29632-43. doi: 10.1074/jbc.M009765200. Epub 2001 May 29. J Biol Chem. 2001. PMID: 11382746 Free article.
109 results