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Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages.
Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW. Kunjathoor VV, et al. Among authors: moore kj. J Biol Chem. 2002 Dec 20;277(51):49982-8. doi: 10.1074/jbc.M209649200. Epub 2002 Oct 9. J Biol Chem. 2002. PMID: 12376530 Free article.
Scavenger receptors in atherosclerosis: beyond lipid uptake.
Moore KJ, Freeman MW. Moore KJ, et al. Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1702-11. doi: 10.1161/01.ATV.0000229218.97976.43. Epub 2006 May 25. Arterioscler Thromb Vasc Biol. 2006. PMID: 16728653 Review.
Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice.
Manning-Tobin JJ, Moore KJ, Seimon TA, Bell SA, Sharuk M, Alvarez-Leite JI, de Winther MP, Tabas I, Freeman MW. Manning-Tobin JJ, et al. Among authors: moore kj. Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):19-26. doi: 10.1161/ATVBAHA.108.176644. Epub 2008 Oct 23. Arterioscler Thromb Vasc Biol. 2009. PMID: 18948635 Free PMC article.
Targeting Innate Immunity for CV Benefit.
Moore KJ, Freeman MW. Moore KJ, et al. Drug Discov Today Ther Strateg. 2008;5(1):15-23. doi: 10.1016/j.ddstr.2008.05.007. Drug Discov Today Ther Strateg. 2008. PMID: 19430537 Free PMC article.
491 results