Freeman MW - Search Results

1

Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages.

Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW. Kunjathoor VV, et al. Among authors: freeman mw. J Biol Chem. 2002 Dec 20;277(51):49982-8. doi: 10.1074/jbc.M209649200. Epub 2002 Oct 9. J Biol Chem. 2002. PMID: 12376530 Free article.

2

Naturally occurring mutations in the largest extracellular loops of ABCA1 can disrupt its direct interaction with apolipoprotein A-I.

Fitzgerald ML, Morris AL, Rhee JS, Andersson LP, Mendez AJ, Freeman MW. Fitzgerald ML, et al. Among authors: freeman mw. J Biol Chem. 2002 Sep 6;277(36):33178-87. doi: 10.1074/jbc.M204996200. Epub 2002 Jun 25. J Biol Chem. 2002. PMID: 12084722 Free article.

3

A CD36-initiated signaling cascade mediates inflammatory effects of beta-amyloid.

Moore KJ, El Khoury J, Medeiros LA, Terada K, Geula C, Luster AD, Freeman MW. Moore KJ, et al. Among authors: freeman mw. J Biol Chem. 2002 Dec 6;277(49):47373-9. doi: 10.1074/jbc.M208788200. Epub 2002 Sep 17. J Biol Chem. 2002. PMID: 12239221 Free article.

4

Abca7 null mice retain normal macrophage phosphatidylcholine and cholesterol efflux activity despite alterations in adipose mass and serum cholesterol levels.

Kim WS, Fitzgerald ML, Kang K, Okuhira K, Bell SA, Manning JJ, Koehn SL, Lu N, Moore KJ, Freeman MW. Kim WS, et al. Among authors: freeman mw. J Biol Chem. 2005 Feb 4;280(5):3989-95. doi: 10.1074/jbc.M412602200. Epub 2004 Nov 17. J Biol Chem. 2005. PMID: 15550377 Free article.

5

Loss of receptor-mediated lipid uptake via scavenger receptor A or CD36 pathways does not ameliorate atherosclerosis in hyperlipidemic mice.

Moore KJ, Kunjathoor VV, Koehn SL, Manning JJ, Tseng AA, Silver JM, McKee M, Freeman MW. Moore KJ, et al. Among authors: freeman mw. J Clin Invest. 2005 Aug;115(8):2192-201. doi: 10.1172/JCI24061. J Clin Invest. 2005. PMID: 16075060 Free PMC article.

6

Scavenger receptors in atherosclerosis: beyond lipid uptake.

Moore KJ, Freeman MW. Moore KJ, et al. Among authors: freeman mw. Arterioscler Thromb Vasc Biol. 2006 Aug;26(8):1702-11. doi: 10.1161/01.ATV.0000229218.97976.43. Epub 2006 May 25. Arterioscler Thromb Vasc Biol. 2006. PMID: 16728653 Review.

7

Functional changes in scavenger receptor binding conformation are induced by charge mutants spanning the entire collagen domain.

Andersson L, Freeman MW. Andersson L, et al. Among authors: freeman mw. J Biol Chem. 1998 Jul 31;273(31):19592-601. doi: 10.1074/jbc.273.31.19592. J Biol Chem. 1998. PMID: 9677385 Free article.

8

Nuclear hormone receptors and cholesterol trafficking: the orphans find a new home.

Fitzgerald ML, Moore KJ, Freeman MW. Fitzgerald ML, et al. Among authors: freeman mw. J Mol Med (Berl). 2002 May;80(5):271-81. doi: 10.1007/s00109-001-0318-y. Epub 2002 Mar 7. J Mol Med (Berl). 2002. PMID: 12021839 Review.

9

Reduced atherosclerosis in MyD88-null mice links elevated serum cholesterol levels to activation of innate immunity signaling pathways.

Björkbacka H, Kunjathoor VV, Moore KJ, Koehn S, Ordija CM, Lee MA, Means T, Halmen K, Luster AD, Golenbock DT, Freeman MW. Björkbacka H, et al. Among authors: freeman mw. Nat Med. 2004 Apr;10(4):416-21. doi: 10.1038/nm1008. Epub 2004 Mar 14. Nat Med. 2004. PMID: 15034566

10

Loss of SR-A and CD36 activity reduces atherosclerotic lesion complexity without abrogating foam cell formation in hyperlipidemic mice.

Manning-Tobin JJ, Moore KJ, Seimon TA, Bell SA, Sharuk M, Alvarez-Leite JI, de Winther MP, Tabas I, Freeman MW. Manning-Tobin JJ, et al. Among authors: freeman mw. Arterioscler Thromb Vasc Biol. 2009 Jan;29(1):19-26. doi: 10.1161/ATVBAHA.108.176644. Epub 2008 Oct 23. Arterioscler Thromb Vasc Biol. 2009. PMID: 18948635 Free PMC article.

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