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Scavenger receptors class A-I/II and CD36 are the principal receptors responsible for the uptake of modified low density lipoprotein leading to lipid loading in macrophages.
Kunjathoor VV, Febbraio M, Podrez EA, Moore KJ, Andersson L, Koehn S, Rhee JS, Silverstein R, Hoff HF, Freeman MW. Kunjathoor VV, et al. Among authors: febbraio m. J Biol Chem. 2002 Dec 20;277(51):49982-8. doi: 10.1074/jbc.M209649200. Epub 2002 Oct 9. J Biol Chem. 2002. PMID: 12376530 Free article.
A novel family of atherogenic oxidized phospholipids promotes macrophage foam cell formation via the scavenger receptor CD36 and is enriched in atherosclerotic lesions.
Podrez EA, Poliakov E, Shen Z, Zhang R, Deng Y, Sun M, Finton PJ, Shan L, Febbraio M, Hajjar DP, Silverstein RL, Hoff HF, Salomon RG, Hazen SL. Podrez EA, et al. Among authors: febbraio m. J Biol Chem. 2002 Oct 11;277(41):38517-23. doi: 10.1074/jbc.M205924200. Epub 2002 Jul 26. J Biol Chem. 2002. PMID: 12145296 Free article.
CD36: implications in cardiovascular disease.
Febbraio M, Silverstein RL. Febbraio M, et al. Int J Biochem Cell Biol. 2007;39(11):2012-30. doi: 10.1016/j.biocel.2007.03.012. Epub 2007 Mar 23. Int J Biochem Cell Biol. 2007. PMID: 17466567 Free PMC article. Review.
Light-induced oxidation of photoreceptor outer segment phospholipids generates ligands for CD36-mediated phagocytosis by retinal pigment epithelium: a potential mechanism for modulating outer segment phagocytosis under oxidant stress conditions.
Sun M, Finnemann SC, Febbraio M, Shan L, Annangudi SP, Podrez EA, Hoppe G, Darrow R, Organisciak DT, Salomon RG, Silverstein RL, Hazen SL. Sun M, et al. Among authors: febbraio m. J Biol Chem. 2006 Feb 17;281(7):4222-30. doi: 10.1074/jbc.M509769200. Epub 2005 Dec 13. J Biol Chem. 2006. PMID: 16354659 Free PMC article.
463 results