Takekawa M - Search Results

1

Usage of tautomycetin, a novel inhibitor of protein phosphatase 1 (PP1), reveals that PP1 is a positive regulator of Raf-1 in vivo.

Mitsuhashi S, Shima H, Tanuma N, Matsuura N, Takekawa M, Urano T, Kataoka T, Ubukata M, Kikuchi K. Mitsuhashi S, et al. Among authors: takekawa m. J Biol Chem. 2003 Jan 3;278(1):82-8. doi: 10.1074/jbc.M208888200. Epub 2002 Oct 8. J Biol Chem. 2003. PMID: 12374792 Free article.

2

A novel low-molecular-mass dual-specificity phosphatase, LDP-2, with a naturally occurring substitution that affects substrate specificity.

Nakamura K, Tanoue K, Satoh T, Takekawa M, Watanabe M, Shima H, Kikuchi K. Nakamura K, et al. Among authors: takekawa m. J Biochem. 2002 Sep;132(3):463-70. doi: 10.1093/oxfordjournals.jbchem.a003244. J Biochem. 2002. PMID: 12204117 Free article.

3

Characterization of a novel low-molecular-mass dual-specificity phosphatase-3 (LDP-3) that enhances activation of JNK and p38.

Takagaki K, Satoh T, Tanuma N, Masuda K, Takekawa M, Shima H, Kikuchi K. Takagaki K, et al. Among authors: takekawa m. Biochem J. 2004 Nov 1;383(Pt. 3):447-55. doi: 10.1042/BJ20040498. Biochem J. 2004. PMID: 15281913 Free PMC article.

4

p53-inducible wip1 phosphatase mediates a negative feedback regulation of p38 MAPK-p53 signaling in response to UV radiation.

Takekawa M, Adachi M, Nakahata A, Nakayama I, Itoh F, Tsukuda H, Taya Y, Imai K. Takekawa M, et al. EMBO J. 2000 Dec 1;19(23):6517-26. doi: 10.1093/emboj/19.23.6517. EMBO J. 2000. PMID: 11101524 Free PMC article.

5

MEK/ERK pathway protects ionizing radiation-induced loss of mitochondrial membrane potential and cell death in lymphocytic leukemia cells.

Shonai T, Adachi M, Sakata K, Takekawa M, Endo T, Imai K, Hareyama M. Shonai T, et al. Among authors: takekawa m. Cell Death Differ. 2002 Sep;9(9):963-71. doi: 10.1038/sj.cdd.4401050. Cell Death Differ. 2002. PMID: 12181747

6

Nuclear export of glucocorticoid receptor is enhanced by c-Jun N-terminal kinase-mediated phosphorylation.

Itoh M, Adachi M, Yasui H, Takekawa M, Tanaka H, Imai K. Itoh M, et al. Among authors: takekawa m. Mol Endocrinol. 2002 Oct;16(10):2382-92. doi: 10.1210/me.2002-0144. Mol Endocrinol. 2002. PMID: 12351702

7

NF-kappaB inhibits TNF-induced accumulation of ROS that mediate prolonged MAPK activation and necrotic cell death.

Sakon S, Xue X, Takekawa M, Sasazuki T, Okazaki T, Kojima Y, Piao JH, Yagita H, Okumura K, Doi T, Nakano H. Sakon S, et al. Among authors: takekawa m. EMBO J. 2003 Aug 1;22(15):3898-909. doi: 10.1093/emboj/cdg379. EMBO J. 2003. PMID: 12881424 Free PMC article.

8

Conserved docking site is essential for activation of mammalian MAP kinase kinases by specific MAP kinase kinase kinases.

Takekawa M, Tatebayashi K, Saito H. Takekawa M, et al. Mol Cell. 2005 Apr 29;18(3):295-306. doi: 10.1016/j.molcel.2005.04.001. Mol Cell. 2005. PMID: 15866172 Free article.

9

Activation of MTK1/MEKK4 by GADD45 through induced N-C dissociation and dimerization-mediated trans autophosphorylation of the MTK1 kinase domain.

Miyake Z, Takekawa M, Ge Q, Saito H. Miyake Z, et al. Among authors: takekawa m. Mol Cell Biol. 2007 Apr;27(7):2765-76. doi: 10.1128/MCB.01435-06. Epub 2007 Jan 22. Mol Cell Biol. 2007. PMID: 17242196 Free PMC article.

10

Qualitative differences in disease-associated MEK mutants reveal molecular signatures and aberrant signaling-crosstalk in cancer.

Kubota Y, Fujioka Y, Patil A, Takagi Y, Matsubara D, Iijima M, Momose I, Naka R, Nakai K, Noda NN, Takekawa M. Kubota Y, et al. Among authors: takekawa m. Nat Commun. 2022 Jul 13;13(1):4063. doi: 10.1038/s41467-022-31690-w. Nat Commun. 2022. PMID: 35831322 Free PMC article.

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