Youdim MB - Search Results

1

Mitochondrial permeability transition mediates apoptosis induced by N-methyl(R)salsolinol, an endogenous neurotoxin, and is inhibited by Bcl-2 and rasagiline, N-propargyl-1(R)-aminoindan.

Akao Y, Maruyama W, Shimizu S, Yi H, Nakagawa Y, Shamoto-Nagai M, Youdim MB, Tsujimoto Y, Naoi M. Akao Y, et al. Among authors: youdim mb. J Neurochem. 2002 Aug;82(4):913-23. doi: 10.1046/j.1471-4159.2002.01047.x. J Neurochem. 2002. PMID: 12358797 Free article.

2

An anti-Parkinson's disease drug, N-propargyl-1(R)-aminoindan (rasagiline), enhances expression of anti-apoptotic bcl-2 in human dopaminergic SH-SY5Y cells.

Akao Y, Maruyama W, Yi H, Shamoto-Nagai M, Youdim MB, Naoi M. Akao Y, et al. Among authors: youdim mb. Neurosci Lett. 2002 Jun 28;326(2):105-8. doi: 10.1016/s0304-3940(02)00332-4. Neurosci Lett. 2002. PMID: 12057839

3

Anti-apoptotic action of anti-Alzheimer drug, TV3326 [(N-propargyl)-(3R)-aminoindan-5-yl]-ethyl methyl carbamate, a novel cholinesterase-monoamine oxidase inhibitor.

Maruyama W, Weinstock M, Youdim MB, Nagai M, Naoi M. Maruyama W, et al. Among authors: youdim mb. Neurosci Lett. 2003 May 8;341(3):233-6. doi: 10.1016/s0304-3940(03)00211-8. Neurosci Lett. 2003. PMID: 12697291

4

Rasagiline: neurodegeneration, neuroprotection, and mitochondrial permeability transition.

Youdim MB, Bar Am O, Yogev-Falach M, Weinreb O, Maruyama W, Naoi M, Amit T. Youdim MB, et al. J Neurosci Res. 2005 Jan 1-15;79(1-2):172-9. doi: 10.1002/jnr.20350. J Neurosci Res. 2005. PMID: 15573406 Review.

5

Neuropharmacological, neuroprotective and amyloid precursor processing properties of selective MAO-B inhibitor antiparkinsonian drug, rasagiline.

Youdim MB, Maruyama W, Naoi M. Youdim MB, et al. Drugs Today (Barc). 2005 Jun;41(6):369-91. doi: 10.1358/dot.2005.41.6.893613. Drugs Today (Barc). 2005. PMID: 16110345 Review.

6

The neuroprotective mechanism of 1-(R)-aminoindan, the major metabolite of the anti-parkinsonian drug rasagiline.

Bar-Am O, Weinreb O, Amit T, Youdim MB. Bar-Am O, et al. Among authors: youdim mb. J Neurochem. 2010 Mar;112(5):1131-7. doi: 10.1111/j.1471-4159.2009.06542.x. Epub 2009 Dec 10. J Neurochem. 2010. PMID: 20002521 Free article. Review.

7

Aminoindan and hydroxyaminoindan, metabolites of rasagiline and ladostigil, respectively, exert neuroprotective properties in vitro.

Bar-Am O, Amit T, Youdim MB. Bar-Am O, et al. Among authors: youdim mb. J Neurochem. 2007 Oct;103(2):500-8. doi: 10.1111/j.1471-4159.2007.04777.x. Epub 2007 Jul 17. J Neurochem. 2007. PMID: 17635668 Free article.

8

Tribute to professor Toshiharu Nagatsu.

Naoi M, Parvez H, Maruyama W, Collins MA, Youdim MB. Naoi M, et al. Among authors: youdim mb. Neurotoxicol Teratol. 2002 Sep-Oct;24(5):563-4. doi: 10.1016/s0892-0362(02)00262-3. Neurotoxicol Teratol. 2002. PMID: 12200186 No abstract available.

9

Regulation of protein kinase C by the anti-Parkinson drug, MAO-B inhibitor, rasagiline and its derivatives, in vivo.

Bar-Am O, Yogev-Falach M, Amit T, Sagi Y, Youdim MB. Bar-Am O, et al. Among authors: youdim mb. J Neurochem. 2004 Jun;89(5):1119-25. doi: 10.1111/j.1471-4159.2004.02425.x. J Neurochem. 2004. PMID: 15147504 Free article.

10

DJ-1 deficiency triggers microglia sensitivity to dopamine toward a pro-inflammatory phenotype that is attenuated by rasagiline.

Trudler D, Weinreb O, Mandel SA, Youdim MB, Frenkel D. Trudler D, et al. Among authors: youdim mb. J Neurochem. 2014 May;129(3):434-47. doi: 10.1111/jnc.12633. Epub 2014 Jan 6. J Neurochem. 2014. PMID: 24355073 Free article.

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