Coll JT - Search Results

1

Crystal structure of aurora-2, an oncogenic serine/threonine kinase.

Cheetham GM, Knegtel RM, Coll JT, Renwick SB, Swenson L, Weber P, Lippke JA, Austen DA. Cheetham GM, et al. Among authors: coll jt. J Biol Chem. 2002 Nov 8;277(45):42419-22. doi: 10.1074/jbc.C200426200. Epub 2002 Sep 16. J Biol Chem. 2002. PMID: 12237287 Free article.

2

Crystal structure of the ectodomain complex of the CGRP receptor, a class-B GPCR, reveals the site of drug antagonism.

ter Haar E, Koth CM, Abdul-Manan N, Swenson L, Coll JT, Lippke JA, Lepre CA, Garcia-Guzman M, Moore JM. ter Haar E, et al. Among authors: coll jt. Structure. 2010 Sep 8;18(9):1083-93. doi: 10.1016/j.str.2010.05.014. Structure. 2010. PMID: 20826335 Free article.

3

The structures of caspases-1, -3, -7 and -8 reveal the basis for substrate and inhibitor selectivity.

Wei Y, Fox T, Chambers SP, Sintchak J, Coll JT, Golec JM, Swenson L, Wilson KP, Charifson PS. Wei Y, et al. Among authors: coll jt. Chem Biol. 2000 Jun;7(6):423-32. doi: 10.1016/s1074-5521(00)00123-x. Chem Biol. 2000. PMID: 10873833

4

Structure of GSK3beta reveals a primed phosphorylation mechanism.

ter Haar E, Coll JT, Austen DA, Hsiao HM, Swenson L, Jain J. ter Haar E, et al. Among authors: coll jt. Nat Struct Biol. 2001 Jul;8(7):593-6. doi: 10.1038/89624. Nat Struct Biol. 2001. PMID: 11427888

5

Development of a protease production platform for structure-based drug design.

Fox T, Brennan D, Austen DA, Swalley SE, Coll JT, Raybuck SA, Chambers SP. Fox T, et al. Among authors: coll jt. Curr Protein Pept Sci. 2007 Oct;8(5):439-45. doi: 10.2174/138920307782411473. Curr Protein Pept Sci. 2007. PMID: 17979759 Review.

6

Refolding and characterization of a soluble ectodomain complex of the calcitonin gene-related peptide receptor.

Koth CM, Abdul-Manan N, Lepre CA, Connolly PJ, Yoo S, Mohanty AK, Lippke JA, Zwahlen J, Coll JT, Doran JD, Garcia-Guzman M, Moore JM. Koth CM, et al. Among authors: coll jt. Biochemistry. 2010 Mar 9;49(9):1862-72. doi: 10.1021/bi901848m. Biochemistry. 2010. PMID: 20099900

7

Nonstructural protein 5A (NS5A) and human replication protein A increase the processivity of hepatitis C virus NS5B polymerase activity in vitro.

Mani N, Yuzhakov A, Yuzhakov O, Coll JT, Black J, Saxena K, Fulghum JR, Lippke JA, Rao BG, Rijnbrand R, Kwong AD. Mani N, et al. Among authors: coll jt. J Virol. 2015 Jan;89(1):165-80. doi: 10.1128/JVI.01677-14. Epub 2014 Oct 15. J Virol. 2015. PMID: 25320291 Free PMC article.

8

Crystal structure of JNK3: a kinase implicated in neuronal apoptosis.

Xie X, Gu Y, Fox T, Coll JT, Fleming MA, Markland W, Caron PR, Wilson KP, Su MS. Xie X, et al. Among authors: coll jt. Structure. 1998 Aug 15;6(8):983-91. doi: 10.1016/s0969-2126(98)00100-2. Structure. 1998. PMID: 9739089 Free article.

9

A single amino acid substitution makes ERK2 susceptible to pyridinyl imidazole inhibitors of p38 MAP kinase.

Fox T, Coll JT, Xie X, Ford PJ, Germann UA, Porter MD, Pazhanisamy S, Fleming MA, Galullo V, Su MS, Wilson KP. Fox T, et al. Among authors: coll jt. Protein Sci. 1998 Nov;7(11):2249-55. doi: 10.1002/pro.5560071102. Protein Sci. 1998. PMID: 9827991 Free PMC article.

10

Fragment-Based Discovery of Dual JC Virus and BK Virus Helicase Inhibitors.

Bonafoux D, Nanthakumar S, Bandarage UK, Memmott C, Lowe D, Aronov AM, Bhisetti GR, Bonanno KC, Coll J, Leeman J, Lepre CA, Lu F, Perola E, Rijnbrand R, Taylor WP, Wilson D, Zhou Y, Zwahlen J, Ter Haar E. Bonafoux D, et al. J Med Chem. 2016 Aug 11;59(15):7138-51. doi: 10.1021/acs.jmedchem.6b00486. Epub 2016 Jul 20. J Med Chem. 2016. PMID: 27385654

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