Kessler H - Search Results

1

Combinatorial and rational strategies to develop nonpeptidic alpha4beta7-integrin antagonists from cyclic peptides.

Gottschling D, Boer J, Schuster A, Holzmann B, Kessler H. Gottschling D, et al. Among authors: kessler h. Angew Chem Int Ed Engl. 2002 Aug 16;41(16):3007-11. doi: 10.1002/1521-3773(20020816)41:16<3007::AID-ANIE3007>3.0.CO;2-3. Angew Chem Int Ed Engl. 2002. PMID: 12203440 No abstract available.

2

Pharmacophore refinement of gpIIb/IIIa antagonists based on comparative studies of antiadhesive cyclic and acyclic RGD peptides.

Müller G, Gurrath M, Kessler H. Müller G, et al. Among authors: kessler h. J Comput Aided Mol Des. 1994 Dec;8(6):709-30. doi: 10.1007/BF00124017. J Comput Aided Mol Des. 1994. PMID: 7738606

3

N-Methylated cyclic RGD peptides as highly active and selective alpha(V)beta(3) integrin antagonists.

Dechantsreiter MA, Planker E, Mathä B, Lohof E, Hölzemann G, Jonczyk A, Goodman SL, Kessler H. Dechantsreiter MA, et al. Among authors: kessler h. J Med Chem. 1999 Aug 12;42(16):3033-40. doi: 10.1021/jm970832g. J Med Chem. 1999. PMID: 10447947

4

Carbohydrate Derivatives for Use in Drug Design: Cyclic alpha(v)-Selective RGD Peptides This work was supported by the Fonds der Chemischen Industrie, the Deutsche Forschungsgemeinschaft, and the Sanderstiftung. The authors thank M. Urzinger, B. Cordes, M. Kranawetter, M. Wolff, and A. Zeller for technical assistance.

Lohof E, Planker E, Mang C, Burkhart F, Dechantsreiter MA, Haubner R, Wester HJ, Schwaiger M, Hölzemann G, Goodman SL, Kessler H. Lohof E, et al. Among authors: kessler h. Angew Chem Int Ed Engl. 2000 Aug 4;39(15):2761-2764. doi: 10.1002/1521-3773(20000804)39:15<2761::aid-anie2761>3.0.co;2-9. Angew Chem Int Ed Engl. 2000. PMID: 10934419 No abstract available.

5

Nonpeptidic alpha(v)beta(3) Integrin Antagonist Libraries: On-Bead Screening and Mass Spectrometric Identification without Tagging The authors acknowledge technical assistance from M. Urzinger, B. Cordes, M. Kranawetter, and A. Schröder. Financial support of the Fonds der Chemischen Industrie and the Deutsche Forschungsgemeinschaft is gratefully acknowledged.

Gibson C, Sulyok GA, Hahn D, Goodman SL, Hölzemann G, Kessler H. Gibson C, et al. Among authors: kessler h. Angew Chem Int Ed Engl. 2001 Jan 5;40(1):165-169. Angew Chem Int Ed Engl. 2001. PMID: 11169701 No abstract available.

6

Solid-phase synthesis of a nonpeptide RGD mimetic library: new selective alphavbeta3 integrin antagonists.

Sulyok GA, Gibson C, Goodman SL, Hölzemann G, Wiesner M, Kessler H. Sulyok GA, et al. Among authors: kessler h. J Med Chem. 2001 Jun 7;44(12):1938-50. doi: 10.1021/jm0004953. J Med Chem. 2001. PMID: 11384239

7

Design and synthesis of potent and selective alpha(4)beta(7) integrin antagonists.

Boer J, Gottschling D, Schuster A, Semmrich M, Holzmann B, Kessler H. Boer J, et al. Among authors: kessler h. J Med Chem. 2001 Aug 2;44(16):2586-92. doi: 10.1021/jm0005508. J Med Chem. 2001. PMID: 11472212

8

Design, Synthesis, and Biological Evaluation of alpha(4)beta(1) Integrin Antagonists Based on beta-D-Mannose as Rigid Scaffold.

Boer J, Gottschling D, Schuster A, Holzmann B, Kessler H. Boer J, et al. Among authors: kessler h. Angew Chem Int Ed Engl. 2001 Oct 15;40(20):3870-3873. Angew Chem Int Ed Engl. 2001. PMID: 11668559 No abstract available.

9

Cellular solid-phase binding assay and mass spectrometry for screening of alpha 4 beta 7 integrin antagonists.

Gottschling D, Boer J, Schuster A, Holzmann B, Kessler H. Gottschling D, et al. Among authors: kessler h. Bioorg Med Chem Lett. 2001 Dec 3;11(23):2997-3000. doi: 10.1016/s0960-894x(01)00611-4. Bioorg Med Chem Lett. 2001. PMID: 11714596

10

Reversible backbone protection enables combinatorial solid-phase ring-closing metathesis reaction (RCM) in peptides.

Schmiedeberg N, Kessler H. Schmiedeberg N, et al. Among authors: kessler h. Org Lett. 2002 Jan 10;4(1):59-62. doi: 10.1021/ol016891c. Org Lett. 2002. PMID: 11772090

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

1,224 results

Search Page

Filters