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Synthesis and pharmacological evaluation of amide conjugates of NSAIDs with L-cysteine ethyl ester, combining potent antiinflammatory and antioxidant properties with significantly reduced gastrointestinal toxicity.
Galanakis D, Kourounakis AP, Tsiakitzis KC, Doulgkeris C, Rekka EA, Gavalas A, Kravaritou C, Charitos C, Kourounakis PN. Galanakis D, et al. Among authors: kourounakis pn, kourounakis ap. Bioorg Med Chem Lett. 2004 Jul 16;14(14):3639-43. doi: 10.1016/j.bmcl.2004.05.025. Bioorg Med Chem Lett. 2004. PMID: 15203134
Synthesis and pharmacochemical study of novel polyfunctional molecules combining anti-inflammatory, antioxidant, and hypocholesterolemic properties.
Doulgkeris CM, Galanakis D, Kourounakis AP, Tsiakitzis KC, Gavalas AM, Eleftheriou PT, Victoratos P, Rekka EA, Kourounakis PN. Doulgkeris CM, et al. Among authors: kourounakis pn, kourounakis ap. Bioorg Med Chem Lett. 2006 Feb 15;16(4):825-9. doi: 10.1016/j.bmcl.2005.11.027. Epub 2005 Nov 23. Bioorg Med Chem Lett. 2006. PMID: 16309906
134 results