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Original 2-(3-Alkoxy-1H-pyrazol-1-yl)azines Inhibitors of Human Dihydroorotate Dehydrogenase (DHODH).
Lucas-Hourani M, Munier-Lehmann H, El Mazouni F, Malmquist NA, Harpon J, Coutant EP, Guillou S, Helynck O, Noel A, Scherf A, Phillips MA, Tangy F, Vidalain PO, Janin YL. Lucas-Hourani M, et al. Among authors: malmquist na. J Med Chem. 2015 Jul 23;58(14):5579-98. doi: 10.1021/acs.jmedchem.5b00606. Epub 2015 Jun 30. J Med Chem. 2015. PMID: 26079043 Free PMC article.
Characterization of Trypanosoma brucei dihydroorotate dehydrogenase as a possible drug target; structural, kinetic and RNAi studies.
Arakaki TL, Buckner FS, Gillespie JR, Malmquist NA, Phillips MA, Kalyuzhniy O, Luft JR, Detitta GT, Verlinde CL, Van Voorhis WC, Hol WG, Merritt EA. Arakaki TL, et al. Among authors: malmquist na. Mol Microbiol. 2008 Apr;68(1):37-50. doi: 10.1111/j.1365-2958.2008.06131.x. Epub 2008 Feb 26. Mol Microbiol. 2008. PMID: 18312275 Free PMC article.
23 results