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Human collagen Krox up-regulates type I collagen expression in normal and scleroderma fibroblasts through interaction with Sp1 and Sp3 transcription factors.
Kypriotou M, Beauchef G, Chadjichristos C, Widom R, Renard E, Jimenez SA, Korn J, Maquart FX, Oddos T, Von Stetten O, Pujol JP, Galéra P. Kypriotou M, et al. Among authors: pujol jp. J Biol Chem. 2007 Nov 2;282(44):32000-14. doi: 10.1074/jbc.M705197200. Epub 2007 Aug 13. J Biol Chem. 2007. PMID: 17698844 Free article.
Interleukin-6 (IL-6) and/or soluble IL-6 receptor down-regulation of human type II collagen gene expression in articular chondrocytes requires a decrease of Sp1.Sp3 ratio and of the binding activity of both factors to the COL2A1 promoter.
Porée B, Kypriotou M, Chadjichristos C, Beauchef G, Renard E, Legendre F, Melin M, Gueret S, Hartmann DJ, Malléin-Gerin F, Pujol JP, Boumediene K, Galéra P. Porée B, et al. Among authors: pujol jp. J Biol Chem. 2008 Feb 22;283(8):4850-65. doi: 10.1074/jbc.M706387200. Epub 2007 Dec 7. J Biol Chem. 2008. PMID: 18065760 Free article.
Chondroitin sulphate decreases collagen synthesis in normal and scleroderma fibroblasts through a Smad-independent TGF-beta pathway--implication of C-Krox and Sp1.
Renard E, Chadjichristos C, Kypriotou M, Beauchef G, Bordat P, Dompmartin A, Widom RL, Boumediene K, Pujol JP, Galéra P. Renard E, et al. Among authors: pujol jp. J Cell Mol Med. 2008 Dec;12(6B):2836-47. doi: 10.1111/j.1582-4934.2008.00287.x. Epub 2008 Feb 24. J Cell Mol Med. 2008. PMID: 18298657 Free PMC article.
129 results