Kirschner MW - Search Results

1

Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck.

Eden S, Rohatgi R, Podtelejnikov AV, Mann M, Kirschner MW. Eden S, et al. Among authors: kirschner mw. Nature. 2002 Aug 15;418(6899):790-3. doi: 10.1038/nature00859. Nature. 2002. PMID: 12181570

2

Separate domains of p21 involved in the inhibition of Cdk kinase and PCNA.

Chen J, Jackson PK, Kirschner MW, Dutta A. Chen J, et al. Among authors: kirschner mw. Nature. 1995 Mar 23;374(6520):386-8. doi: 10.1038/374386a0. Nature. 1995. PMID: 7885482

3

The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42.

Ma L, Rohatgi R, Kirschner MW. Ma L, et al. Among authors: kirschner mw. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15362-7. doi: 10.1073/pnas.95.26.15362. Proc Natl Acad Sci U S A. 1998. PMID: 9860974 Free PMC article.

4

The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly.

Rohatgi R, Ma L, Miki H, Lopez M, Kirchhausen T, Takenawa T, Kirschner MW. Rohatgi R, et al. Among authors: kirschner mw. Cell. 1999 Apr 16;97(2):221-31. doi: 10.1016/s0092-8674(00)80732-1. Cell. 1999. PMID: 10219243 Free article.

5

Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate.

Rohatgi R, Ho HY, Kirschner MW. Rohatgi R, et al. Among authors: kirschner mw. J Cell Biol. 2000 Sep 18;150(6):1299-310. doi: 10.1083/jcb.150.6.1299. J Cell Biol. 2000. PMID: 10995436 Free PMC article.

6

Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway.

Rohatgi R, Nollau P, Ho HY, Kirschner MW, Mayer BJ. Rohatgi R, et al. Among authors: kirschner mw. J Biol Chem. 2001 Jul 13;276(28):26448-52. doi: 10.1074/jbc.M103856200. Epub 2001 May 4. J Biol Chem. 2001. PMID: 11340081 Free article.

7

CR16 forms a complex with N-WASP in brain and is a novel member of a conserved proline-rich actin-binding protein family.

Ho HY, Rohatgi R, Ma L, Kirschner MW. Ho HY, et al. Among authors: kirschner mw. Proc Natl Acad Sci U S A. 2001 Sep 25;98(20):11306-11. doi: 10.1073/pnas.211420498. Epub 2001 Sep 11. Proc Natl Acad Sci U S A. 2001. PMID: 11553796 Free PMC article.

8

A chemical inhibitor of N-WASP reveals a new mechanism for targeting protein interactions.

Peterson JR, Lokey RS, Mitchison TJ, Kirschner MW. Peterson JR, et al. Among authors: kirschner mw. Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10624-9. doi: 10.1073/pnas.201393198. Proc Natl Acad Sci U S A. 2001. PMID: 11553809 Free PMC article.

9

Anaphase specific auto-cleavage of separase.

Zou H, Stemman O, Anderson JS, Mann M, Kirschner MW. Zou H, et al. Among authors: kirschner mw. FEBS Lett. 2002 Sep 25;528(1-3):246-50. doi: 10.1016/s0014-5793(02)03238-6. FEBS Lett. 2002. PMID: 12297314 Free article.

10

WAVE2 deficiency reveals distinct roles in embryogenesis and Rac-mediated actin-based motility.

Yan C, Martinez-Quiles N, Eden S, Shibata T, Takeshima F, Shinkura R, Fujiwara Y, Bronson R, Snapper SB, Kirschner MW, Geha R, Rosen FS, Alt FW. Yan C, et al. Among authors: kirschner mw. EMBO J. 2003 Jul 15;22(14):3602-12. doi: 10.1093/emboj/cdg350. EMBO J. 2003. PMID: 12853475 Free PMC article.

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