Goldstein JA - Search Results

1

Regulation of human CYP2C9 by the constitutive androstane receptor: discovery of a new distal binding site.

Ferguson SS, LeCluyse EL, Negishi M, Goldstein JA. Ferguson SS, et al. Among authors: goldstein ja. Mol Pharmacol. 2002 Sep;62(3):737-46. doi: 10.1124/mol.62.3.737. Mol Pharmacol. 2002. PMID: 12181452

2

Discovery of new potentially defective alleles of human CYP2C9.

Blaisdell J, Jorge-Nebert LF, Coulter S, Ferguson SS, Lee SJ, Chanas B, Xi T, Mohrenweiser H, Ghanayem B, Goldstein JA. Blaisdell J, et al. Among authors: goldstein ja. Pharmacogenetics. 2004 Aug;14(8):527-37. doi: 10.1097/01.fpc.0000114759.08559.51. Pharmacogenetics. 2004. PMID: 15284535

3

Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.

Ferguson SS, Chen Y, LeCluyse EL, Negishi M, Goldstein JA. Ferguson SS, et al. Among authors: goldstein ja. Mol Pharmacol. 2005 Sep;68(3):747-57. doi: 10.1124/mol.105.013169. Epub 2005 Jun 2. Mol Pharmacol. 2005. PMID: 15933212

4

Phenytoin induction of the cyp2c37 gene is mediated by the constitutive androstane receptor.

Jackson JP, Ferguson SS, Negishi M, Goldstein JA. Jackson JP, et al. Among authors: goldstein ja. Drug Metab Dispos. 2006 Dec;34(12):2003-10. doi: 10.1124/dmd.106.012005. Epub 2006 Aug 25. Drug Metab Dispos. 2006. PMID: 16936065 Free PMC article.

5

The nuclear receptors constitutive active/androstane receptor and pregnane x receptor activate the Cyp2c55 gene in mouse liver.

Konno Y, Kamino H, Moore R, Lih F, Tomer KB, Zeldin DC, Goldstein JA, Negishi M. Konno Y, et al. Among authors: goldstein ja. Drug Metab Dispos. 2010 Jul;38(7):1177-82. doi: 10.1124/dmd.110.032334. Epub 2010 Apr 6. Drug Metab Dispos. 2010. PMID: 20371638 Free PMC article.

6

Human CYP2C8 is post-transcriptionally regulated by microRNAs 103 and 107 in human liver.

Zhang SY, Surapureddi S, Coulter S, Ferguson SS, Goldstein JA. Zhang SY, et al. Among authors: goldstein ja. Mol Pharmacol. 2012 Sep;82(3):529-40. doi: 10.1124/mol.112.078386. Epub 2012 Jun 20. Mol Pharmacol. 2012. PMID: 22723340 Free PMC article.

7

Identification of constitutive androstane receptor and glucocorticoid receptor binding sites in the CYP2C19 promoter.

Chen Y, Ferguson SS, Negishi M, Goldstein JA. Chen Y, et al. Among authors: goldstein ja. Mol Pharmacol. 2003 Aug;64(2):316-24. doi: 10.1124/mol.64.2.316. Mol Pharmacol. 2003. PMID: 12869636

8

Induction of human CYP2C9 by rifampicin, hyperforin, and phenobarbital is mediated by the pregnane X receptor.

Chen Y, Ferguson SS, Negishi M, Goldstein JA. Chen Y, et al. Among authors: goldstein ja. J Pharmacol Exp Ther. 2004 Feb;308(2):495-501. doi: 10.1124/jpet.103.058818. Epub 2003 Nov 4. J Pharmacol Exp Ther. 2004. PMID: 14600250

9

The constitutive active/androstane receptor regulates phenytoin induction of Cyp2c29.

Jackson JP, Ferguson SS, Moore R, Negishi M, Goldstein JA. Jackson JP, et al. Among authors: goldstein ja. Mol Pharmacol. 2004 Jun;65(6):1397-404. doi: 10.1124/mol.65.6.1397. Mol Pharmacol. 2004. PMID: 15155833

10

The nuclear receptors constitutive androstane receptor and pregnane X receptor cross-talk with hepatic nuclear factor 4alpha to synergistically activate the human CYP2C9 promoter.

Chen Y, Kissling G, Negishi M, Goldstein JA. Chen Y, et al. Among authors: goldstein ja. J Pharmacol Exp Ther. 2005 Sep;314(3):1125-33. doi: 10.1124/jpet.105.087072. Epub 2005 May 26. J Pharmacol Exp Ther. 2005. PMID: 15919766

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