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The short apical membrane half-life of rescued {Delta}F508-cystic fibrosis transmembrane conductance regulator (CFTR) results from accelerated endocytosis of {Delta}F508-CFTR in polarized human airway epithelial cells.
Swiatecka-Urban A, Brown A, Moreau-Marquis S, Renuka J, Coutermarsh B, Barnaby R, Karlson KH, Flotte TR, Fukuda M, Langford GM, Stanton BA. Swiatecka-Urban A, et al. Among authors: karlson kh. J Biol Chem. 2005 Nov 4;280(44):36762-72. doi: 10.1074/jbc.M508944200. Epub 2005 Aug 30. J Biol Chem. 2005. PMID: 16131493 Free article.
Myosin Vb is required for trafficking of the cystic fibrosis transmembrane conductance regulator in Rab11a-specific apical recycling endosomes in polarized human airway epithelial cells.
Swiatecka-Urban A, Talebian L, Kanno E, Moreau-Marquis S, Coutermarsh B, Hansen K, Karlson KH, Barnaby R, Cheney RE, Langford GM, Fukuda M, Stanton BA. Swiatecka-Urban A, et al. Among authors: karlson kh. J Biol Chem. 2007 Aug 10;282(32):23725-36. doi: 10.1074/jbc.M608531200. Epub 2007 Apr 26. J Biol Chem. 2007. PMID: 17462998 Free article.
Membrane trafficking of the cystic fibrosis gene product, cystic fibrosis transmembrane conductance regulator, tagged with green fluorescent protein in madin-darby canine kidney cells.
Moyer BD, Loffing J, Schwiebert EM, Loffing-Cueni D, Halpin PA, Karlson KH, Ismailov II, Guggino WB, Langford GM, Stanton BA. Moyer BD, et al. Among authors: karlson kh. J Biol Chem. 1998 Aug 21;273(34):21759-68. doi: 10.1074/jbc.273.34.21759. J Biol Chem. 1998. PMID: 9705313 Free article.
A PDZ-interacting domain in CFTR is an apical membrane polarization signal.
Moyer BD, Denton J, Karlson KH, Reynolds D, Wang S, Mickle JE, Milewski M, Cutting GR, Guggino WB, Li M, Stanton BA. Moyer BD, et al. Among authors: karlson kh. J Clin Invest. 1999 Nov;104(10):1353-61. doi: 10.1172/JCI7453. J Clin Invest. 1999. PMID: 10562297 Free PMC article.
The PDZ-interacting domain of cystic fibrosis transmembrane conductance regulator is required for functional expression in the apical plasma membrane.
Moyer BD, Duhaime M, Shaw C, Denton J, Reynolds D, Karlson KH, Pfeiffer J, Wang S, Mickle JE, Milewski M, Cutting GR, Guggino WB, Li M, Stanton BA. Moyer BD, et al. Among authors: karlson kh. J Biol Chem. 2000 Sep 1;275(35):27069-74. doi: 10.1074/jbc.M004951200. J Biol Chem. 2000. PMID: 10852925 Free article.
37 results