Pearce W - Search Results

1

Impaired B and T cell antigen receptor signaling in p110delta PI 3-kinase mutant mice.

Okkenhaug K, Bilancio A, Farjot G, Priddle H, Sancho S, Peskett E, Pearce W, Meek SE, Salpekar A, Waterfield MD, Smith AJ, Vanhaesebroeck B. Okkenhaug K, et al. Among authors: pearce w. Science. 2002 Aug 9;297(5583):1031-4. doi: 10.1126/science.1073560. Epub 2002 Jul 18. Science. 2002. PMID: 12130661

2

Essential role for the p110delta phosphoinositide 3-kinase in the allergic response.

Ali K, Bilancio A, Thomas M, Pearce W, Gilfillan AM, Tkaczyk C, Kuehn N, Gray A, Giddings J, Peskett E, Fox R, Bruce I, Walker C, Sawyer C, Okkenhaug K, Finan P, Vanhaesebroeck B. Ali K, et al. Among authors: pearce w. Nature. 2004 Oct 21;431(7011):1007-11. doi: 10.1038/nature02991. Nature. 2004. PMID: 15496927 Free article.

3

Airway inflammation: chemokine-induced neutrophilia and the class I phosphoinositide 3-kinases.

Thomas MJ, Smith A, Head DH, Milne L, Nicholls A, Pearce W, Vanhaesebroeck B, Wymann MP, Hirsch E, Trifilieff A, Walker C, Finan P, Westwick J. Thomas MJ, et al. Among authors: pearce w. Eur J Immunol. 2005 Apr;35(4):1283-91. doi: 10.1002/eji.200425634. Eur J Immunol. 2005. PMID: 15739165 Free article.

4

Role of the p110delta PI 3-kinase in integrin and ITAM receptor signalling in platelets.

Senis YA, Atkinson BT, Pearce AC, Wonerow P, Auger JM, Okkenhaug K, Pearce W, Vigorito E, Vanhaesebroeck B, Turner M, Watson SP. Senis YA, et al. Among authors: pearce ac, pearce w. Platelets. 2005 May-Jun;16(3-4):191-202. doi: 10.1080/09537100400016711. Platelets. 2005. PMID: 16011964 Free PMC article.

5

Critical role for the p110alpha phosphoinositide-3-OH kinase in growth and metabolic regulation.

Foukas LC, Claret M, Pearce W, Okkenhaug K, Meek S, Peskett E, Sancho S, Smith AJ, Withers DJ, Vanhaesebroeck B. Foukas LC, et al. Among authors: pearce w. Nature. 2006 May 18;441(7091):366-70. doi: 10.1038/nature04694. Epub 2006 Apr 12. Nature. 2006. PMID: 16625210

6

Ultrasensitive and absolute quantification of the phosphoinositide 3-kinase/Akt signal transduction pathway by mass spectrometry.

Cutillas PR, Khwaja A, Graupera M, Pearce W, Gharbi S, Waterfield M, Vanhaesebroeck B. Cutillas PR, et al. Among authors: pearce w. Proc Natl Acad Sci U S A. 2006 Jun 13;103(24):8959-64. doi: 10.1073/pnas.0602101103. Epub 2006 Jun 2. Proc Natl Acad Sci U S A. 2006. PMID: 16751276 Free PMC article.

7

Cutting edge: the phosphoinositide 3-kinase p110 delta is critical for the function of CD4+CD25+Foxp3+ regulatory T cells.

Patton DT, Garden OA, Pearce WP, Clough LE, Monk CR, Leung E, Rowan WC, Sancho S, Walker LS, Vanhaesebroeck B, Okkenhaug K. Patton DT, et al. J Immunol. 2006 Nov 15;177(10):6598-602. doi: 10.4049/jimmunol.177.10.6598. J Immunol. 2006. PMID: 17082571

8

Inactivation of PI3Kgamma and PI3Kdelta distorts T-cell development and causes multiple organ inflammation.

Ji H, Rintelen F, Waltzinger C, Bertschy Meier D, Bilancio A, Pearce W, Hirsch E, Wymann MP, Rückle T, Camps M, Vanhaesebroeck B, Okkenhaug K, Rommel C. Ji H, et al. Among authors: pearce w. Blood. 2007 Oct 15;110(8):2940-7. doi: 10.1182/blood-2007-04-086751. Epub 2007 Jul 12. Blood. 2007. PMID: 17626838 Free article.

9

Control of axonal growth and regeneration of sensory neurons by the p110delta PI 3-kinase.

Eickholt BJ, Ahmed AI, Davies M, Papakonstanti EA, Pearce W, Starkey ML, Bilancio A, Need AC, Smith AJ, Hall SM, Hamers FP, Giese KP, Bradbury EJ, Vanhaesebroeck B. Eickholt BJ, et al. Among authors: pearce w. PLoS One. 2007 Sep 11;2(9):e869. doi: 10.1371/journal.pone.0000869. PLoS One. 2007. PMID: 17846664 Free PMC article.

10

Isoform-specific functions of phosphoinositide 3-kinases: p110 delta but not p110 gamma promotes optimal allergic responses in vivo.

Ali K, Camps M, Pearce WP, Ji H, Rückle T, Kuehn N, Pasquali C, Chabert C, Rommel C, Vanhaesebroeck B. Ali K, et al. J Immunol. 2008 Feb 15;180(4):2538-44. doi: 10.4049/jimmunol.180.4.2538. J Immunol. 2008. PMID: 18250464 Free PMC article.

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