Saini SK - Search Results

1

Identification of a novel partial inhibitor of dopamine transporter among 4-substituted 2-phenylquinazolines.

Ananthan S, Saini SK, Khare R, Clayton SD, Dersch CM, Rothman RB. Ananthan S, et al. Among authors: saini sk. Bioorg Med Chem Lett. 2002 Aug 19;12(16):2225-8. doi: 10.1016/s0960-894x(02)00348-7. Bioorg Med Chem Lett. 2002. PMID: 12127543

2

Synthesis, opioid receptor binding, and functional activity of 5'-substituted 17-cyclopropylmethylpyrido[2',3':6,7]morphinans.

Ananthan S, Kezar HS 3rd, Saini SK, Khare NK, Davis P, Dersch CM, Porreca F, Rothman RB. Ananthan S, et al. Among authors: saini sk. Bioorg Med Chem Lett. 2003 Feb 10;13(3):529-32. doi: 10.1016/s0960-894x(02)00934-4. Bioorg Med Chem Lett. 2003. PMID: 12565965

3

Novel ligands for the opioid receptors: synthesis and structure-activity relationships among 5'-aryl and 5'-heteroaryl 17-cyclopropylmethyl-4,5 alpha-epoxypyrido[2',3':6,7]morphinans.

Ananthan S, Khare NK, Saini SK, Davis P, Dersch CM, Porreca F, Rothman RB. Ananthan S, et al. Among authors: saini sk. Bioorg Med Chem. 2003 Sep 1;11(18):4143-54. doi: 10.1016/s0968-0896(03)00432-2. Bioorg Med Chem. 2003. PMID: 12927876

4

Identification of opioid ligands possessing mixed micro agonist/delta antagonist activity among pyridomorphinans derived from naloxone, oxymorphone, and hydromorphone [correction of hydropmorphone].

Ananthan S, Khare NK, Saini SK, Seitz LE, Bartlett JL, Davis P, Dersch CM, Porreca F, Rothman RB, Bilsky EJ. Ananthan S, et al. Among authors: saini sk. J Med Chem. 2004 Mar 11;47(6):1400-12. doi: 10.1021/jm030311v. J Med Chem. 2004. PMID: 14998329

5

14-Alkoxy- and 14-acyloxypyridomorphinans: μ agonist/δ antagonist opioid analgesics with diminished tolerance and dependence side effects.

Ananthan S, Saini SK, Dersch CM, Xu H, McGlinchey N, Giuvelis D, Bilsky EJ, Rothman RB. Ananthan S, et al. Among authors: saini sk. J Med Chem. 2012 Oct 11;55(19):8350-63. doi: 10.1021/jm300686p. Epub 2012 Sep 27. J Med Chem. 2012. PMID: 23016952 Free PMC article.

6

Studies of the biogenic amine transporters 15. Identification of novel allosteric dopamine transporter ligands with nanomolar potency.

Rothman RB, Ananthan S, Partilla JS, Saini SK, Moukha-Chafiq O, Pathak V, Baumann MH. Rothman RB, et al. Among authors: saini sk. J Pharmacol Exp Ther. 2015 Jun;353(3):529-38. doi: 10.1124/jpet.114.222299. Epub 2015 Mar 18. J Pharmacol Exp Ther. 2015. PMID: 25788711 Free PMC article.

7

Synthesis, opioid receptor binding, and biological activities of naltrexone-derived pyrido- and pyrimidomorphinans.

Ananthan S, Kezar HS 3rd, Carter RL, Saini SK, Rice KC, Wells JL, Davis P, Xu H, Dersch CM, Bilsky EJ, Porreca F, Rothman RB. Ananthan S, et al. Among authors: saini sk. J Med Chem. 1999 Sep 9;42(18):3527-38. doi: 10.1021/jm990039i. J Med Chem. 1999. PMID: 10479286

8

Design, synthesis, and structure-activity relationship studies of a series of [4-(4-carboxamidobutyl)]-1-arylpiperazines: insights into structural features contributing to dopamine D3 versus D2 receptor subtype selectivity.

Ananthan S, Saini SK, Zhou G, Hobrath JV, Padmalayam I, Zhai L, Bostwick JR, Antonio T, Reith ME, McDowell S, Cho E, McAleer L, Taylor M, Luedtke RR. Ananthan S, et al. Among authors: saini sk. J Med Chem. 2014 Aug 28;57(16):7042-60. doi: 10.1021/jm500801r. Epub 2014 Aug 15. J Med Chem. 2014. PMID: 25126833 Free PMC article.

9

Interactions between Cocaine and the Putative Allosteric Dopamine Transporter Ligand SRI-31142.

Moerke MJ, Ananthan S, Banks ML, Eltit JM, Freitas KC, Johnson AR, Saini SK, Steele TWE, Negus SS. Moerke MJ, et al. Among authors: saini sk. J Pharmacol Exp Ther. 2018 Nov;367(2):222-233. doi: 10.1124/jpet.118.250902. Epub 2018 Aug 27. J Pharmacol Exp Ther. 2018. PMID: 30150482 Free PMC article.

10

Synthesis and Structure-Activity Relationships of 5'-Aryl-14-alkoxypyridomorphinans: Identification of a μ Opioid Receptor Agonist/δ Opioid Receptor Antagonist Ligand with Systemic Antinociceptive Activity and Diminished Opioid Side Effects.

Vekariya RH, Lei W, Ray A, Saini SK, Zhang S, Molnar G, Barlow D, Karlage KL, Bilsky EJ, Houseknecht KL, Largent-Milnes TM, Streicher JM, Ananthan S. Vekariya RH, et al. Among authors: saini sk. J Med Chem. 2020 Jul 23;63(14):7663-7694. doi: 10.1021/acs.jmedchem.0c00503. Epub 2020 Jun 30. J Med Chem. 2020. PMID: 32530286 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

112 results

Search Page

Filters