Sawyers CL - Search Results

1

The phosphatidylinositol 3-Kinase AKT pathway in human cancer.

Vivanco I, Sawyers CL. Vivanco I, et al. Among authors: sawyers cl. Nat Rev Cancer. 2002 Jul;2(7):489-501. doi: 10.1038/nrc839. Nat Rev Cancer. 2002. PMID: 12094235 Review. No abstract available.

2

The PTEN/MMAC1 tumor suppressor phosphatase functions as a negative regulator of the phosphoinositide 3-kinase/Akt pathway.

Wu X, Senechal K, Neshat MS, Whang YE, Sawyers CL. Wu X, et al. Among authors: sawyers cl. Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15587-91. doi: 10.1073/pnas.95.26.15587. Proc Natl Acad Sci U S A. 1998. PMID: 9861013 Free PMC article.

3

A mechanism for hormone-independent prostate cancer through modulation of androgen receptor signaling by the HER-2/neu tyrosine kinase.

Craft N, Shostak Y, Carey M, Sawyers CL. Craft N, et al. Among authors: sawyers cl. Nat Med. 1999 Mar;5(3):280-5. doi: 10.1038/6495. Nat Med. 1999. PMID: 10086382

4

Mechanistic concepts in androgen-dependence of prostate cancer.

Craft N, Sawyers CL. Craft N, et al. Among authors: sawyers cl. Cancer Metastasis Rev. 1998-1999;17(4):421-7. doi: 10.1023/a:1006141806801. Cancer Metastasis Rev. 1998. PMID: 10453286 Review.

5

The survival function of the Bcr-Abl oncogene is mediated by Bad-dependent and -independent pathways: roles for phosphatidylinositol 3-kinase and Raf.

Neshat MS, Raitano AB, Wang HG, Reed JC, Sawyers CL. Neshat MS, et al. Among authors: sawyers cl. Mol Cell Biol. 2000 Feb;20(4):1179-86. doi: 10.1128/MCB.20.4.1179-1186.2000. Mol Cell Biol. 2000. PMID: 10648603 Free PMC article.

6

Growth inhibitory effects of the dual ErbB1/ErbB2 tyrosine kinase inhibitor PKI-166 on human prostate cancer xenografts.

Mellinghoff IK, Tran C, Sawyers CL. Mellinghoff IK, et al. Among authors: sawyers cl. Cancer Res. 2002 Sep 15;62(18):5254-9. Cancer Res. 2002. PMID: 12234993

7

Analysis of the phosphatidylinositol 3'-kinase signaling pathway in glioblastoma patients in vivo.

Choe G, Horvath S, Cloughesy TF, Crosby K, Seligson D, Palotie A, Inge L, Smith BL, Sawyers CL, Mischel PS. Choe G, et al. Among authors: sawyers cl. Cancer Res. 2003 Jun 1;63(11):2742-6. Cancer Res. 2003. PMID: 12782577

8

Myc-driven murine prostate cancer shares molecular features with human prostate tumors.

Ellwood-Yen K, Graeber TG, Wongvipat J, Iruela-Arispe ML, Zhang J, Matusik R, Thomas GV, Sawyers CL. Ellwood-Yen K, et al. Among authors: sawyers cl. Cancer Cell. 2003 Sep;4(3):223-38. doi: 10.1016/s1535-6108(03)00197-1. Cancer Cell. 2003. PMID: 14522256 Free article.

9

Will mTOR inhibitors make it as cancer drugs?

Sawyers CL. Sawyers CL. Cancer Cell. 2003 Nov;4(5):343-8. doi: 10.1016/s1535-6108(03)00275-7. Cancer Cell. 2003. PMID: 14667501 Free article. Review. No abstract available.

10

HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability.

Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. Mellinghoff IK, et al. Among authors: sawyers cl. Cancer Cell. 2004 Nov;6(5):517-27. doi: 10.1016/j.ccr.2004.09.031. Cancer Cell. 2004. PMID: 15542435 Free article.

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