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Safety, tolerability, pharmacokinetics, and time course of pharmacologic response of the active metabolite of roxifiban, XV459, a glycoprotein IIb/IIIa antagonist, following oral administration in healthy volunteers.
Pieniaszek HJ Jr, Sy SK, Ebling W, Fossler MJ, Cain VA, Mondick JT, Ma S, Kornhauser DM. Pieniaszek HJ Jr, et al. Among authors: kornhauser dm. J Clin Pharmacol. 2002 Jul;42(7):738-53. doi: 10.1177/009127002401102687. J Clin Pharmacol. 2002. PMID: 12092741 Clinical Trial.
Effects of the glycoprotein IIb/IIIa antagonist Roxifiban on P-selectin expression, fibrinogen binding, and microaggregate formation in a phase I dose-finding study: no evidence for platelet activation during treatment with a glycoprotein IIb/IIIa antagonist.
Seiffert D, Thomas BE, Bradley JD, Munzer DA, Tchinnes MA, Kornhauser DM, Cain VA, Hua TA, Feuerstein GZ, Martin DE, Stern AM. Seiffert D, et al. Among authors: kornhauser dm. Platelets. 2003 May;14(3):179-87. doi: 10.1080/0953710031000092820. Platelets. 2003. PMID: 12850842 Free article. Clinical Trial.
42 results