Der CJ - Search Results

1

Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation.

Pruitt K, Pruitt WM, Bilter GK, Westwick JK, Der CJ. Pruitt K, et al. Among authors: der cj. J Biol Chem. 2002 Aug 30;277(35):31808-17. doi: 10.1074/jbc.M203964200. Epub 2002 Jun 24. J Biol Chem. 2002. PMID: 12082106 Free article.

2

Ras (CXXX) and Rab (CC/CXC) prenylation signal sequences are unique and functionally distinct.

Khosravi-Far R, Clark GJ, Abe K, Cox AD, McLain T, Lutz RJ, Sinensky M, Der CJ. Khosravi-Far R, et al. Among authors: der cj. J Biol Chem. 1992 Dec 5;267(34):24363-8. J Biol Chem. 1992. PMID: 1332953 Free article.

3

Activation of Rac1, RhoA, and mitogen-activated protein kinases is required for Ras transformation.

Khosravi-Far R, Solski PA, Clark GJ, Kinch MS, Der CJ. Khosravi-Far R, et al. Among authors: der cj. Mol Cell Biol. 1995 Nov;15(11):6443-53. doi: 10.1128/MCB.15.11.6443. Mol Cell Biol. 1995. PMID: 7565796 Free PMC article.

4

Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes.

Lerner EC, Qian Y, Blaskovich MA, Fossum RD, Vogt A, Sun J, Cox AD, Der CJ, Hamilton AD, Sebti SM. Lerner EC, et al. Among authors: der cj. J Biol Chem. 1995 Nov 10;270(45):26802-6. doi: 10.1074/jbc.270.45.26802. J Biol Chem. 1995. PMID: 7592920 Free article.

5

Aberrant function of the Ras signal transduction pathway in human breast cancer.

Clark GJ, Der CJ. Clark GJ, et al. Among authors: der cj. Breast Cancer Res Treat. 1995 Jul;35(1):133-44. doi: 10.1007/BF00694753. Breast Cancer Res Treat. 1995. PMID: 7612899 Review.

6

Two distinct Raf domains mediate interaction with Ras.

Brtva TR, Drugan JK, Ghosh S, Terrell RS, Campbell-Burk S, Bell RM, Der CJ. Brtva TR, et al. Among authors: der cj. J Biol Chem. 1995 Apr 28;270(17):9809-12. doi: 10.1074/jbc.270.17.9809. J Biol Chem. 1995. PMID: 7730360 Free article.

7

Biological assays for cellular transformation.

Cox AD, Der CJ. Cox AD, et al. Among authors: der cj. Methods Enzymol. 1994;238:277-94. doi: 10.1016/0076-6879(94)38026-0. Methods Enzymol. 1994. PMID: 7799794

8

Dbl and Vav mediate transformation via mitogen-activated protein kinase pathways that are distinct from those activated by oncogenic Ras.

Khosravi-Far R, Chrzanowska-Wodnicka M, Solski PA, Eva A, Burridge K, Der CJ. Khosravi-Far R, et al. Among authors: der cj. Mol Cell Biol. 1994 Oct;14(10):6848-57. doi: 10.1128/mcb.14.10.6848-6857.1994. Mol Cell Biol. 1994. PMID: 7935402 Free PMC article.

9

R-Ras induces malignant, but not morphologic, transformation of NIH3T3 cells.

Cox AD, Brtva TR, Lowe DG, Der CJ. Cox AD, et al. Among authors: der cj. Oncogene. 1994 Nov;9(11):3281-8. Oncogene. 1994. PMID: 7936652

10

Oncogenic Ras activates c-Jun via a separate pathway from the activation of extracellular signal-regulated kinases.

Westwick JK, Cox AD, Der CJ, Cobb MH, Hibi M, Karin M, Brenner DA. Westwick JK, et al. Among authors: der cj. Proc Natl Acad Sci U S A. 1994 Jun 21;91(13):6030-4. doi: 10.1073/pnas.91.13.6030. Proc Natl Acad Sci U S A. 1994. PMID: 8016110 Free PMC article.

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