Sletta H - Search Results

1

High-yield actinorhodin production in fed-batch culture by a Streptomyces lividans strain overexpressing the pathway-specific activator gene actll-ORF4.

Bruheim P, Sletta H, Bibb MJ, White J, Levine DW. Bruheim P, et al. Among authors: sletta h. J Ind Microbiol Biotechnol. 2002 Feb;28(2):103-11. doi: 10.1038/sj/jim/7000219. J Ind Microbiol Biotechnol. 2002. PMID: 12074050

2

Molecular cloning and analysis of a pleiotropic regulatory gene locus from the nystatin producer Streptomyces noursei ATCC11455.

Sekurova O, Sletta H, Ellingsen TE, Valla S, Zotchev S. Sekurova O, et al. Among authors: sletta h. FEMS Microbiol Lett. 1999 Aug 15;177(2):297-304. doi: 10.1111/j.1574-6968.1999.tb13746.x. FEMS Microbiol Lett. 1999. PMID: 10474196

3

Identification of a gene cluster for antibacterial polyketide-derived antibiotic biosynthesis in the nystatin producer Streptomyces noursei ATCC 11455.

Zotchev S, Haugan K, Sekurova O, Sletta H, Ellingsen TE, Valla S. Zotchev S, et al. Among authors: sletta h. Microbiology (Reading). 2000 Mar;146 ( Pt 3):611-619. doi: 10.1099/00221287-146-3-611. Microbiology (Reading). 2000. PMID: 10746764 Free article.

4

Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.

Brautaset T, Sekurova ON, Sletta H, Ellingsen TE, StrŁm AR, Valla S, Zotchev SB. Brautaset T, et al. Among authors: sletta h. Chem Biol. 2000 Jun;7(6):395-403. doi: 10.1016/s1074-5521(00)00120-4. Chem Biol. 2000. PMID: 10873841

5

Hexaene derivatives of nystatin produced as a result of an induced rearrangement within the nysC polyketide synthase gene in S. noursei ATCC 11455.

Brautaset T, Bruheim P, Sletta H, Hagen L, Ellingsen TE, Strøm AR, Valla S, Zotchev SB. Brautaset T, et al. Among authors: sletta h. Chem Biol. 2002 Mar;9(3):367-73. doi: 10.1016/s1074-5521(02)00108-4. Chem Biol. 2002. PMID: 11927262

6

In vivo analysis of the regulatory genes in the nystatin biosynthetic gene cluster of Streptomyces noursei ATCC 11455 reveals their differential control over antibiotic biosynthesis.

Sekurova ON, Brautaset T, Sletta H, Borgos SE, Jakobsen M ØM, Ellingsen TE, Strøm AR, Valla S, Zotchev SB. Sekurova ON, et al. Among authors: sletta h. J Bacteriol. 2004 Mar;186(5):1345-54. doi: 10.1128/JB.186.5.1345-1354.2004. J Bacteriol. 2004. PMID: 14973031 Free PMC article.

7

Chemical diversity of polyene macrolides produced by Streptomyces noursei ATCC 11455 and recombinant strain ERD44 with genetically altered polyketide synthase NysC.

Bruheim P, Borgos SE, Tsan P, Sletta H, Ellingsen TE, Lancelin JM, Zotchev SB. Bruheim P, et al. Among authors: sletta h. Antimicrob Agents Chemother. 2004 Nov;48(11):4120-9. doi: 10.1128/AAC.48.11.4120-4129.2004. Antimicrob Agents Chemother. 2004. PMID: 15504830 Free PMC article.

8

Nystatin biosynthesis and transport: nysH and nysG genes encoding a putative ABC transporter system in Streptomyces noursei ATCC 11455 are required for efficient conversion of 10-deoxynystatin to nystatin.

Sletta H, Borgos SE, Bruheim P, Sekurova ON, Grasdalen H, Aune R, Ellingsen TE, Zotchev SB. Sletta H, et al. Antimicrob Agents Chemother. 2005 Nov;49(11):4576-83. doi: 10.1128/AAC.49.11.4576-4583.2005. Antimicrob Agents Chemother. 2005. PMID: 16251298 Free PMC article.

9

Effect of glucose limitation and specific mutations in the module 5 enoyl reductase domains in the nystatin and amphotericin polyketide synthases on polyene macrolide biosynthesis.

Borgos SE, Sletta H, Fjaervik E, Brautaset T, Ellingsen TE, Gulliksen OM, Zotchev SB. Borgos SE, et al. Among authors: sletta h. Arch Microbiol. 2006 Apr;185(3):165-71. doi: 10.1007/s00203-005-0083-3. Epub 2006 Jan 14. Arch Microbiol. 2006. PMID: 16416127

10

Characterization of the P450 monooxygenase NysL, responsible for C-10 hydroxylation during biosynthesis of the polyene macrolide antibiotic nystatin in Streptomyces noursei.

Volokhan O, Sletta H, Ellingsen TE, Zotchev SB. Volokhan O, et al. Among authors: sletta h. Appl Environ Microbiol. 2006 Apr;72(4):2514-9. doi: 10.1128/AEM.72.4.2514-2519.2006. Appl Environ Microbiol. 2006. PMID: 16597951 Free PMC article.

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