Zheng H - Search Results

1

The aspartate-257 of presenilin 1 is indispensable for mouse development and production of beta-amyloid peptides through beta-catenin-independent mechanisms.

Xia X, Wang P, Sun X, Soriano S, Shum WK, Yamaguchi H, Trumbauer ME, Takashima A, Koo EH, Zheng H. Xia X, et al. Among authors: zheng h. Proc Natl Acad Sci U S A. 2002 Jun 25;99(13):8760-5. doi: 10.1073/pnas.132045399. Epub 2002 Jun 17. Proc Natl Acad Sci U S A. 2002. PMID: 12070348 Free PMC article.

2

Accelerated plaque accumulation, associative learning deficits, and up-regulation of alpha 7 nicotinic receptor protein in transgenic mice co-expressing mutant human presenilin 1 and amyloid precursor proteins.

Dineley KT, Xia X, Bui D, Sweatt JD, Zheng H. Dineley KT, et al. Among authors: zheng h. J Biol Chem. 2002 Jun 21;277(25):22768-80. doi: 10.1074/jbc.M200164200. Epub 2002 Mar 23. J Biol Chem. 2002. PMID: 11912199 Free article.

3

Presenilin-1 mutations of leucine 166 equally affect the generation of the Notch and APP intracellular domains independent of their effect on Abeta 42 production.

Moehlmann T, Winkler E, Xia X, Edbauer D, Murrell J, Capell A, Kaether C, Zheng H, Ghetti B, Haass C, Steiner H. Moehlmann T, et al. Among authors: zheng h. Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):8025-30. doi: 10.1073/pnas.112686799. Epub 2002 Jun 4. Proc Natl Acad Sci U S A. 2002. PMID: 12048239 Free PMC article.

4

Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis.

Kang DE, Soriano S, Xia X, Eberhart CG, De Strooper B, Zheng H, Koo EH. Kang DE, et al. Among authors: zheng h. Cell. 2002 Sep 20;110(6):751-62. doi: 10.1016/s0092-8674(02)00970-4. Cell. 2002. PMID: 12297048 Free article.

5

Presenilins are required for the formation of comma- and S-shaped bodies during nephrogenesis.

Wang P, Pereira FA, Beasley D, Zheng H. Wang P, et al. Among authors: zheng h. Development. 2003 Oct;130(20):5019-29. doi: 10.1242/dev.00682. Epub 2003 Aug 20. Development. 2003. PMID: 12930775

6

Ghrelin stimulation of growth hormone release and appetite is mediated through the growth hormone secretagogue receptor.

Sun Y, Wang P, Zheng H, Smith RG. Sun Y, et al. Among authors: zheng h. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4679-84. doi: 10.1073/pnas.0305930101. Epub 2004 Mar 18. Proc Natl Acad Sci U S A. 2004. PMID: 15070777 Free PMC article.

7

Myeloproliferative disease in mice with reduced presenilin gene dosage: effect of gamma-secretase blockage.

Qyang Y, Chambers SM, Wang P, Xia X, Chen X, Goodell MA, Zheng H. Qyang Y, et al. Among authors: zheng h. Biochemistry. 2004 May 11;43(18):5352-9. doi: 10.1021/bi049826u. Biochemistry. 2004. PMID: 15122901

8

Regulation of tyrosinase trafficking and processing by presenilins: partial loss of function by familial Alzheimer's disease mutation.

Wang R, Tang P, Wang P, Boissy RE, Zheng H. Wang R, et al. Among authors: zheng h. Proc Natl Acad Sci U S A. 2006 Jan 10;103(2):353-8. doi: 10.1073/pnas.0509822102. Epub 2005 Dec 29. Proc Natl Acad Sci U S A. 2006. PMID: 16384915 Free PMC article.

9

The amyloid precursor protein: beyond amyloid.

Zheng H, Koo EH. Zheng H, et al. Mol Neurodegener. 2006 Jul 3;1:5. doi: 10.1186/1750-1326-1-5. Mol Neurodegener. 2006. PMID: 16930452 Free PMC article.

10

Biology and pathophysiology of the amyloid precursor protein.

Zheng H, Koo EH. Zheng H, et al. Mol Neurodegener. 2011 Apr 28;6(1):27. doi: 10.1186/1750-1326-6-27. Mol Neurodegener. 2011. PMID: 21527012 Free PMC article.

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