Hanson SR - Search Results

1

The thrombin mutant W215A/E217A shows safe and potent anticoagulant and antithrombotic effects in vivo.

Gruber A, Cantwell AM, Di Cera E, Hanson SR. Gruber A, et al. Among authors: hanson sr. J Biol Chem. 2002 Aug 2;277(31):27581-4. doi: 10.1074/jbc.C200237200. Epub 2002 Jun 17. J Biol Chem. 2002. PMID: 12070133 Free article.

2

Potential new targets for antithrombotic therapy.

Gruber A, Hanson SR. Gruber A, et al. Among authors: hanson sr. Curr Pharm Des. 2003;9(28):2367-74. doi: 10.2174/1381612033453938. Curr Pharm Des. 2003. PMID: 14529397 Review.

3

Limited generation of activated protein C during infusion of the protein C activator thrombin analog W215A/E217A in primates.

Gruber A, Fernández JA, Bush L, Marzec U, Griffin JH, Hanson SR, DI Cera E. Gruber A, et al. Among authors: hanson sr. J Thromb Haemost. 2006 Feb;4(2):392-7. doi: 10.1111/j.1538-7836.2006.01760.x. J Thromb Haemost. 2006. PMID: 16420571 Free article.

4

Factor XI-dependence of surface- and tissue factor-initiated thrombus propagation in primates.

Gruber A, Hanson SR. Gruber A, et al. Among authors: hanson sr. Blood. 2003 Aug 1;102(3):953-5. doi: 10.1182/blood-2003-01-0324. Epub 2003 Apr 10. Blood. 2003. PMID: 12689935 Free article.

5

Soluble thrombomodulin is antithrombotic in the presence of neutralising antibodies to protein C and reduces circulating activated protein C levels in primates.

Tanaka KA, Fernández JA, Marzec UM, Kelly AB, Mohri M, Griffin JH, Hanson SR, Gruber A. Tanaka KA, et al. Among authors: hanson sr. Br J Haematol. 2006 Jan;132(2):197-203. doi: 10.1111/j.1365-2141.2005.05855.x. Br J Haematol. 2006. PMID: 16398653 Free article.

6

Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates.

Gruber A, Marzec UM, Bush L, Di Cera E, Fernández JA, Berny MA, Tucker EI, McCarty OJ, Griffin JH, Hanson SR. Gruber A, et al. Among authors: hanson sr. Blood. 2007 May 1;109(9):3733-40. doi: 10.1182/blood-2006-07-035147. Epub 2007 Jan 16. Blood. 2007. PMID: 17227834 Free PMC article.

7

Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor.

Tanaka KA, Gruber A, Szlam F, Bush LA, Hanson SR, Di Cera E. Tanaka KA, et al. Among authors: hanson sr. Blood Coagul Fibrinolysis. 2008 Jul;19(5):465-8. doi: 10.1097/MBC.0b013e328304e044. Blood Coagul Fibrinolysis. 2008. PMID: 18600103 Free PMC article. No abstract available.

8

Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI.

Tucker EI, Marzec UM, White TC, Hurst S, Rugonyi S, McCarty OJ, Gailani D, Gruber A, Hanson SR. Tucker EI, et al. Among authors: hanson sr. Blood. 2009 Jan 22;113(4):936-44. doi: 10.1182/blood-2008-06-163675. Epub 2008 Oct 22. Blood. 2009. PMID: 18945968 Free PMC article.

9

Antithrombotic effects of thrombin-induced activation of endogenous protein C in primates.

Hanson SR, Griffin JH, Harker LA, Kelly AB, Esmon CT, Gruber A. Hanson SR, et al. J Clin Invest. 1993 Oct;92(4):2003-12. doi: 10.1172/JCI116795. J Clin Invest. 1993. PMID: 8408654 Free PMC article.

10

Hemostatic effect of activated factor VII without promotion of thrombus growth in melagatran-anticoagulated primates.

Gruber A, Carlsson S, Kotzé HF, Marzec U, Sarich TC, Hanson SR. Gruber A, et al. Among authors: hanson sr. Thromb Res. 2007;119(1):121-7. doi: 10.1016/j.thromres.2005.12.002. Epub 2006 Jan 31. Thromb Res. 2007. PMID: 16448687

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