Rajamani S - Search Results

1

Pharmacological rescue of human K(+) channel long-QT2 mutations: human ether-a-go-go-related gene rescue without block.

Rajamani S, Anderson CL, Anson BD, January CT. Rajamani S, et al. Circulation. 2002 Jun 18;105(24):2830-5. doi: 10.1161/01.cir.0000019513.50928.74. Circulation. 2002. PMID: 12070109

2

The anti-malarial drug halofantrine and its metabolite N-desbutylhalofantrine block HERG potassium channels.

Mbai M, Rajamani S, January CT. Mbai M, et al. Among authors: rajamani s. Cardiovasc Res. 2002 Sep;55(4):799-805. doi: 10.1016/s0008-6363(02)00448-0. Cardiovasc Res. 2002. PMID: 12176129

3

Biology of cardiac arrhythmias: ion channel protein trafficking.

Delisle BP, Anson BD, Rajamani S, January CT. Delisle BP, et al. Among authors: rajamani s. Circ Res. 2004 Jun 11;94(11):1418-28. doi: 10.1161/01.RES.0000128561.28701.ea. Circ Res. 2004. PMID: 15192037 Review.

4

Protein trafficking abnormalities: a new mechanism in drug-induced long QT syndrome.

Eckhardt LL, Rajamani S, January CT. Eckhardt LL, et al. Among authors: rajamani s. Br J Pharmacol. 2005 May;145(1):3-4. doi: 10.1038/sj.bjp.0706143. Br J Pharmacol. 2005. PMID: 15711590 Free PMC article.

5

Specific serine proteases selectively damage KCNH2 (hERG1) potassium channels and I(Kr).

Rajamani S, Anderson CL, Valdivia CR, Eckhardt LL, Foell JD, Robertson GA, Kamp TJ, Makielski JC, Anson BD, January CT. Rajamani S, et al. Am J Physiol Heart Circ Physiol. 2006 Mar;290(3):H1278-88. doi: 10.1152/ajpheart.00777.2005. Epub 2005 Oct 14. Am J Physiol Heart Circ Physiol. 2006. PMID: 16227340 Free article.

6

Drug-induced long QT syndrome: hERG K+ channel block and disruption of protein trafficking by fluoxetine and norfluoxetine.

Rajamani S, Eckhardt LL, Valdivia CR, Klemens CA, Gillman BM, Anderson CL, Holzem KM, Delisle BP, Anson BD, Makielski JC, January CT. Rajamani S, et al. Br J Pharmacol. 2006 Nov;149(5):481-9. doi: 10.1038/sj.bjp.0706892. Epub 2006 Sep 11. Br J Pharmacol. 2006. PMID: 16967046 Free PMC article.

7

Genetic basis for the origin of cardiac arrhythmias: implications for therapy.

Mbai M, Rajamani S, Delisle BP, Anson BD, Anderson C, Makielski JC, January CT. Mbai M, et al. Among authors: rajamani s. Curr Cardiol Rep. 2002 Sep;4(5):411-7. doi: 10.1007/s11886-002-0041-5. Curr Cardiol Rep. 2002. PMID: 12169238 Review.

8

Cocaine blocks HERG, but not KvLQT1+minK, potassium channels.

Zhang S, Rajamani S, Chen Y, Gong Q, Rong Y, Zhou Z, Ruoho A, January CT. Zhang S, et al. Among authors: rajamani s. Mol Pharmacol. 2001 May;59(5):1069-76. doi: 10.1124/mol.59.5.1069. Mol Pharmacol. 2001. PMID: 11306689

9

Reduction of repolarization reserve unmasks the proarrhythmic role of endogenous late Na(+) current in the heart.

Wu L, Rajamani S, Li H, January CT, Shryock JC, Belardinelli L. Wu L, et al. Among authors: rajamani s. Am J Physiol Heart Circ Physiol. 2009 Sep;297(3):H1048-57. doi: 10.1152/ajpheart.00467.2009. Epub 2009 Jul 10. Am J Physiol Heart Circ Physiol. 2009. PMID: 19592609 Free article.

10

Mutations in SCN10A are responsible for a large fraction of cases of Brugada syndrome.

Hu D, Barajas-Martínez H, Pfeiffer R, Dezi F, Pfeiffer J, Buch T, Betzenhauser MJ, Belardinelli L, Kahlig KM, Rajamani S, DeAntonio HJ, Myerburg RJ, Ito H, Deshmukh P, Marieb M, Nam GB, Bhatia A, Hasdemir C, Haïssaguerre M, Veltmann C, Schimpf R, Borggrefe M, Viskin S, Antzelevitch C. Hu D, et al. Among authors: rajamani s. J Am Coll Cardiol. 2014 Jul 8;64(1):66-79. doi: 10.1016/j.jacc.2014.04.032. J Am Coll Cardiol. 2014. PMID: 24998131 Free PMC article.

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