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Small-molecule-induced ERBB4 activation to treat heart failure.
Cools JMT, Goovaerts BK, Feyen E, Van den Bogaert S, Fu Y, Civati C, Van Fraeyenhove J, Tubeeckx MRL, Ott J, Nguyen L, Wülfers EM, Van Berlo B, De Vries AAF, Vandersickel N, Pijnappels DA, Audenaert D, Roderick HL, De Winter H, De Keulenaer GW, Segers VFM. Cools JMT, et al. Among authors: de winter h. Nat Commun. 2025 Jan 10;16(1):576. doi: 10.1038/s41467-024-54908-5. Nat Commun. 2025. PMID: 39794341 Free PMC article.
Discovery and Development of an Advanced Lead for the Treatment of African Trypanosomiasis.
Ilbeigi K, Mabille D, Matheeussen A, Hendrickx R, Claes M, Van Reet N, Anthonissen R, Hulpia F, Lin C, Maes L, Regnault C, Whitfield P, Roy R, Ungogo MA, Sterckx YG, De Winter H, Mertens B, Bundschuh M, De Koning HP, Van Calenbergh S, Caljon G. Ilbeigi K, et al. Among authors: de winter h. ACS Infect Dis. 2025 Jan 10;11(1):131-143. doi: 10.1021/acsinfecdis.4c00472. Epub 2024 Dec 12. ACS Infect Dis. 2025. PMID: 39665421
Pharmacological modulation of septins restores calcium homeostasis and is neuroprotective in models of Alzheimer's disease.
Princen K, Van Dooren T, van Gorsel M, Louros N, Yang X, Dumbacher M, Bastiaens I, Coupet K, Dupont S, Cuveliers E, Lauwers A, Laghmouchi M, Vanwelden T, Carmans S, Van Damme N, Duhamel H, Vansteenkiste S, Prerad J, Pipeleers K, Rodiers O, De Ridder L, Claes S, Busschots Y, Pringels L, Verhelst V, Debroux E, Brouwer M, Lievens S, Tavernier J, Farinelli M, Hughes-Asceri S, Voets M, Winderickx J, Wera S, de Wit J, Schymkowitz J, Rousseau F, Zetterberg H, Cummings JL, Annaert W, Cornelissen T, De Winter H, De Witte K, Fivaz M, Griffioen G. Princen K, et al. Among authors: de winter h. Science. 2024 May 31;384(6699):eadd6260. doi: 10.1126/science.add6260. Epub 2024 May 31. Science. 2024. PMID: 38815015
70 results