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Page 1
8-Methoxyquinolines as PDE4 inhibitors.
Billah M, Buckley GM, Cooper N, Dyke HJ, Egan R, Ganguly A, Gowers L, Haughan AF, Kendall HJ, Lowe C, Minnicozzi M, Montana JG, Oxford J, Peake JC, Picken CL, Piwinski JJ, Naylor R, Sabin V, Shih NY, Warneck JB. Billah M, et al. Among authors: ganguly a. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1617-9. doi: 10.1016/s0960-894x(02)00224-x. Bioorg Med Chem Lett. 2002. PMID: 12039575
Pharmacology of N-(3,5-dichloro-1-oxido-4-pyridinyl)-8-methoxy-2-(trifluoromethyl)-5-quinoline carboxamide (SCH 351591), a novel, orally active phosphodiesterase 4 inhibitor.
Billah MM, Cooper N, Minnicozzi M, Warneck J, Wang P, Hey JA, Kreutner W, Rizzo CA, Smith SR, Young S, Chapman RW, Dyke H, Shih NY, Piwinski JJ, Cuss FM, Montana J, Ganguly AK, Egan RW. Billah MM, et al. Among authors: ganguly ak. J Pharmacol Exp Ther. 2002 Jul;302(1):127-37. doi: 10.1124/jpet.302.1.127. J Pharmacol Exp Ther. 2002. PMID: 12065709 Clinical Trial.
Synthesis and profile of SCH351591, a novel PDE4 inhibitor.
Billah M, Cooper N, Cuss F, Davenport RJ, Dyke HJ, Egan R, Ganguly A, Gowers L, Hannah DR, Haughan AF, Kendall HJ, Lowe C, Minnicozzi M, Montana JG, Naylor R, Oxford J, Peake JC, Piwinski JJ, Runcie KA, Sabin V, Sharpe A, Shih NY, Warneck JB. Billah M, et al. Among authors: ganguly a. Bioorg Med Chem Lett. 2002 Jun 17;12(12):1621-3. doi: 10.1016/s0960-894x(02)00225-1. Bioorg Med Chem Lett. 2002. PMID: 12039576
Dual antagonists of platelet activating factor and histamine. 3. Synthesis, biological activity and conformational implications of substituted N-acyl-bis-arylcycloheptapiperazines.
Piwinski JJ, Wong JK, Green MJ, Kaminski JJ, Colizzo F, Albanese MM, Ganguly AK, Billah MM, Anthes JC, West RE Jr. Piwinski JJ, et al. Among authors: ganguly ak. Bioorg Med Chem Lett. 1998 Dec 15;8(24):3469-74. doi: 10.1016/s0960-894x(98)00626-x. Bioorg Med Chem Lett. 1998. PMID: 9934454
Discovery of (1R,5S)-N-[3-amino-1-(cyclobutylmethyl)-2,3-dioxopropyl]- 3-[2(S)-[[[(1,1-dimethylethyl)amino]carbonyl]amino]-3,3-dimethyl-1-oxobutyl]- 6,6-dimethyl-3-azabicyclo[3.1.0]hexan-2(S)-carboxamide (SCH 503034), a selective, potent, orally bioavailable hepatitis C virus NS3 protease inhibitor: a potential therapeutic agent for the treatment of hepatitis C infection.
Venkatraman S, Bogen SL, Arasappan A, Bennett F, Chen K, Jao E, Liu YT, Lovey R, Hendrata S, Huang Y, Pan W, Parekh T, Pinto P, Popov V, Pike R, Ruan S, Santhanam B, Vibulbhan B, Wu W, Yang W, Kong J, Liang X, Wong J, Liu R, Butkiewicz N, Chase R, Hart A, Agrawal S, Ingravallo P, Pichardo J, Kong R, Baroudy B, Malcolm B, Guo Z, Prongay A, Madison V, Broske L, Cui X, Cheng KC, Hsieh Y, Brisson JM, Prelusky D, Korfmacher W, White R, Bogdanowich-Knipp S, Pavlovsky A, Bradley P, Saksena AK, Ganguly A, Piwinski J, Girijavallabhan V, Njoroge FG. Venkatraman S, et al. Among authors: ganguly a. J Med Chem. 2006 Oct 5;49(20):6074-86. doi: 10.1021/jm060325b. J Med Chem. 2006. PMID: 17004721
Discovery of novel nonpeptide tricyclic inhibitors of Ras farnesyl protein transferase.
Njoroge FG, Doll RJ, Vibulbhan B, Alvarez CS, Bishop WR, Petrin J, Kirschmeier P, Carruthers NI, Wong JK, Albanese MM, Piwinski JJ, Catino J, Girijavallabhan V, Ganguly AK. Njoroge FG, et al. Among authors: ganguly ak. Bioorg Med Chem. 1997 Jan;5(1):101-13. doi: 10.1016/s0968-0896(96)00206-4. Bioorg Med Chem. 1997. PMID: 9043662
Tricyclic farnesyl protein transferase inhibitors: crystallographic and calorimetric studies of structure-activity relationships.
Strickland CL, Weber PC, Windsor WT, Wu Z, Le HV, Albanese MM, Alvarez CS, Cesarz D, del Rosario J, Deskus J, Mallams AK, Njoroge FG, Piwinski JJ, Remiszewski S, Rossman RR, Taveras AG, Vibulbhan B, Doll RJ, Girijavallabhan VM, Ganguly AK. Strickland CL, et al. Among authors: ganguly ak. J Med Chem. 1999 Jun 17;42(12):2125-35. doi: 10.1021/jm990030g. J Med Chem. 1999. PMID: 10377218
1,056 results