Rosen N - Search Results

1

Degradation of HER2 by ansamycins induces growth arrest and apoptosis in cells with HER2 overexpression via a HER3, phosphatidylinositol 3'-kinase-AKT-dependent pathway.

Münster PN, Marchion DC, Basso AD, Rosen N. Münster PN, et al. Among authors: rosen n. Cancer Res. 2002 Jun 1;62(11):3132-7. Cancer Res. 2002. PMID: 12036925

2

Insulin-like growth factor II mRNA expression in human breast cancer.

Yee D, Cullen KJ, Paik S, Perdue JF, Hampton B, Schwartz A, Lippman ME, Rosen N. Yee D, et al. Among authors: rosen n. Cancer Res. 1988 Dec 1;48(23):6691-6. Cancer Res. 1988. PMID: 3180080

3

A peptidomimetic inhibitor of farnesyl:protein transferase blocks the anchorage-dependent and -independent growth of human tumor cell lines.

Sepp-Lorenzino L, Ma Z, Rands E, Kohl NE, Gibbs JB, Oliff A, Rosen N. Sepp-Lorenzino L, et al. Among authors: rosen n. Cancer Res. 1995 Nov 15;55(22):5302-9. Cancer Res. 1995. PMID: 7585592

4

p53Val135 temperature sensitive mutant suppresses growth of human breast cancer cells.

Eliyahu D, Evans S, Rosen N, Eliyahu S, Zwiebel J, Paik S, Lippman M. Eliyahu D, et al. Among authors: rosen n. Breast Cancer Res Treat. 1994;30(2):167-77. doi: 10.1007/BF00666061. Breast Cancer Res Treat. 1994. PMID: 7949216

5

Cyclin D expression is controlled post-transcriptionally via a phosphatidylinositol 3-kinase/Akt-dependent pathway.

Muise-Helmericks RC, Grimes HL, Bellacosa A, Malstrom SE, Tsichlis PN, Rosen N. Muise-Helmericks RC, et al. Among authors: rosen n. J Biol Chem. 1998 Nov 6;273(45):29864-72. doi: 10.1074/jbc.273.45.29864. J Biol Chem. 1998. PMID: 9792703 Free article.

6

Constitutive overexpression of cyclin D1 in human breast epithelial cells does not prevent G1 arrest induced by deprivation of epidermal growth factor.

Chou JL, Fan Z, DeBlasio T, Koff A, Rosen N, Mendelsohn J. Chou JL, et al. Among authors: rosen n. Breast Cancer Res Treat. 1999 Jun;55(3):267-83. doi: 10.1023/a:1006217413089. Breast Cancer Res Treat. 1999. PMID: 10517171

7

Inhibition of Src kinases by a selective tyrosine kinase inhibitor causes mitotic arrest.

Moasser MM, Srethapakdi M, Sachar KS, Kraker AJ, Rosen N. Moasser MM, et al. Among authors: rosen n. Cancer Res. 1999 Dec 15;59(24):6145-52. Cancer Res. 1999. PMID: 10626805

8

Identification of a geldanamycin dimer that induces the selective degradation of HER-family tyrosine kinases.

Zheng FF, Kuduk SD, Chiosis G, Münster PN, Sepp-Lorenzino L, Danishefsky SJ, Rosen N. Zheng FF, et al. Among authors: rosen n. Cancer Res. 2000 Apr 15;60(8):2090-4. Cancer Res. 2000. PMID: 10786665

9

Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.

Srethapakdi M, Liu F, Tavorath R, Rosen N. Srethapakdi M, et al. Among authors: rosen n. Cancer Res. 2000 Jul 15;60(14):3940-6. Cancer Res. 2000. PMID: 10919672

10

A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells.

Chiosis G, Timaul MN, Lucas B, Munster PN, Zheng FF, Sepp-Lorenzino L, Rosen N. Chiosis G, et al. Among authors: rosen n. Chem Biol. 2001 Mar;8(3):289-99. doi: 10.1016/s1074-5521(01)00015-1. Chem Biol. 2001. PMID: 11306353

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