Wise LD - Search Results

1

A new type of prodrug of catecholamines: an opportunity to improve the treatment of Parkinson's disease.

Venhuis BJ, Rodenhuis N, Wikström HV, Wustrow D, Meltzer LT, Wise LD, Johnson SJ, Pugsley TA, Sundell S, Dijkstra D. Venhuis BJ, et al. Among authors: wise ld. J Med Chem. 2002 Jun 6;45(12):2349-51. doi: 10.1021/jm025508m. J Med Chem. 2002. PMID: 12036342

2

Further characterization of structural requirements for ligands at the dopamine D(2) and D(3) receptor: exploring the thiophene moiety.

Dijkstra D, Rodenhuis N, Vermeulen ES, Pugsley TA, Wise LD, Wikström HV. Dijkstra D, et al. Among authors: wise ld. J Med Chem. 2002 Jul 4;45(14):3022-31. doi: 10.1021/jm001015a. J Med Chem. 2002. PMID: 12086487

3

Orally active analogues of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one: synthesis and pharmacological activity.

Venhuis BJ, Dijkstra D, Wustrow DJ, Meltzer LT, Wise LD, Johnson SJ, Heffner TG, Wikström HV. Venhuis BJ, et al. Among authors: wise ld. J Med Chem. 2003 Feb 13;46(4):584-90. doi: 10.1021/jm020990u. J Med Chem. 2003. PMID: 12570379

4

Orally active oxime derivatives of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one. Synthesis and pharmacological activity.

Venhuis BJ, Dijkstra D, Wustrow D, Meltzer LT, Wise LD, Johnson SJ, Wikström HV. Venhuis BJ, et al. Among authors: wise ld. J Med Chem. 2003 Sep 11;46(19):4136-40. doi: 10.1021/jm0307786. J Med Chem. 2003. PMID: 12954065

5

Affinity for dopamine D2, D3, and D4 receptors of 2-aminotetralins. Relevance of D2 agonist binding for determination of receptor subtype selectivity.

van Vliet LA, Tepper PG, Dijkstra D, Damsma G, Wikström H, Pugsley TA, Akunne HC, Heffner TG, Glase SA, Wise LD. van Vliet LA, et al. Among authors: wise ld. J Med Chem. 1996 Oct 11;39(21):4233-7. doi: 10.1021/jm960345l. J Med Chem. 1996. PMID: 8863800

6

Synthesis and pharmacological evaluation of thiopyran analogues of the dopamine D3 receptor-selective agonist (4aR,10bR)-(+)-trans-3,4,4a,10b-tetrahydro-4-n-propyl-2H,5H [1]b enzopyrano[4,3-b]-1,4-oxazin-9-ol (PD 128907).

van Vliet LA, Rodenhuis N, Dijkstra D, Wikström H, Pugsley TA, Serpa KA, Meltzer LT, Heffner TG, Wise LD, Lajiness ME, Huff RM, Svensson K, Sundell S, Lundmark M. van Vliet LA, et al. Among authors: wise ld. J Med Chem. 2000 Jul 27;43(15):2871-82. doi: 10.1021/jm0000113. J Med Chem. 2000. PMID: 10956195

7

Thiazoloindans and thiazolobenzopyrans: a novel class of orally active central dopamine (partial) agonists.

van Vliet LA, Rodenhuis N, Wikström H, Pugsley TA, Serpa KA, Meltzer LT, Heffner TG, Wise LD, Lajiness ME, Huff RM, Svensson K, Haenen GR, Bast A. van Vliet LA, et al. Among authors: wise ld. J Med Chem. 2000 Sep 21;43(19):3549-57. doi: 10.1021/jm000087z. J Med Chem. 2000. PMID: 11000009

8

Aminopyrimidines with high affinity for both serotonin and dopamine receptors.

Wustrow D, Belliotti T, Glase S, Kesten SR, Johnson D, Colbry N, Rubin R, Blackburn A, Akunne H, Corbin A, Davis MD, Georgic L, Whetzel S, Zoski K, Heffner T, Pugsley T, Wise L. Wustrow D, et al. J Med Chem. 1998 Feb 26;41(5):760-71. doi: 10.1021/jm9707378. J Med Chem. 1998. PMID: 9513604

9

Dopamine autoreceptor agonists as potential antipsychotics. 2. (Aminoalkoxy)-4H-1-benzopyran-4-ones.

Jaen JC, Wise LD, Heffner TG, Pugsley TA, Meltzer LT. Jaen JC, et al. Among authors: wise ld. J Med Chem. 1991 Jan;34(1):248-56. doi: 10.1021/jm00105a039. J Med Chem. 1991. PMID: 1671416

10

Dopamine autoreceptor agonists as potential antipsychotics. 3.6-Propyl-4,5,5a,6,7,8-hexahydrothiazolo[4,5-f]quinolin-2-amine.

Caprathe BW, Jaen JC, Wise LD, Heffner TG, Pugsley TA, Meltzer LT, Parvez M. Caprathe BW, et al. Among authors: wise ld. J Med Chem. 1991 Sep;34(9):2736-46. doi: 10.1021/jm00113a010. J Med Chem. 1991. PMID: 1680195

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