Dijkstra D - Search Results

1

A new type of prodrug of catecholamines: an opportunity to improve the treatment of Parkinson's disease.

Venhuis BJ, Rodenhuis N, Wikström HV, Wustrow D, Meltzer LT, Wise LD, Johnson SJ, Pugsley TA, Sundell S, Dijkstra D. Venhuis BJ, et al. Among authors: dijkstra d. J Med Chem. 2002 Jun 6;45(12):2349-51. doi: 10.1021/jm025508m. J Med Chem. 2002. PMID: 12036342

2

Further characterization of structural requirements for ligands at the dopamine D(2) and D(3) receptor: exploring the thiophene moiety.

Dijkstra D, Rodenhuis N, Vermeulen ES, Pugsley TA, Wise LD, Wikström HV. Dijkstra D, et al. J Med Chem. 2002 Jul 4;45(14):3022-31. doi: 10.1021/jm001015a. J Med Chem. 2002. PMID: 12086487

3

Orally active analogues of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one: synthesis and pharmacological activity.

Venhuis BJ, Dijkstra D, Wustrow DJ, Meltzer LT, Wise LD, Johnson SJ, Heffner TG, Wikström HV. Venhuis BJ, et al. Among authors: dijkstra d. J Med Chem. 2003 Feb 13;46(4):584-90. doi: 10.1021/jm020990u. J Med Chem. 2003. PMID: 12570379

4

Orally active oxime derivatives of the dopaminergic prodrug 6-(N,N-di-n-propylamino)-3,4,5,6,7,8-hexahydro-2H-naphthalen-1-one. Synthesis and pharmacological activity.

Venhuis BJ, Dijkstra D, Wustrow D, Meltzer LT, Wise LD, Johnson SJ, Wikström HV. Venhuis BJ, et al. Among authors: dijkstra d. J Med Chem. 2003 Sep 11;46(19):4136-40. doi: 10.1021/jm0307786. J Med Chem. 2003. PMID: 12954065

5

Extremely potent orally active benzo[g]quinoline analogue of the dopaminergic prodrug: 1-propyl-trans-2,3,4,4a,5,7,8,9,10,10a-decahydro-1H-benzo-[g]quinolin-6-one [corrected].

Liu D, Wikström HV, Dijkstra D, de Vries JB, Venhuis BJ. Liu D, et al. Among authors: dijkstra d. J Med Chem. 2006 Feb 23;49(4):1494-8. doi: 10.1021/jm051111h. J Med Chem. 2006. PMID: 16480286

6

A novel synthesis and pharmacological evaluation of a potential dopamine D1/D2 agonist: 1-propyl-1,2,3,4,4a,5,10,10a-octahydrobenzo[g]quinoline-6,7-diol.

Liu D, Dijkstra D, de Vries JB, Wikström HV. Liu D, et al. Among authors: dijkstra d. Bioorg Med Chem. 2008 Mar 15;16(6):3438-44. doi: 10.1016/j.bmc.2007.06.036. Epub 2007 Jun 23. Bioorg Med Chem. 2008. PMID: 18313303

7

Affinity for dopamine D2, D3, and D4 receptors of 2-aminotetralins. Relevance of D2 agonist binding for determination of receptor subtype selectivity.

van Vliet LA, Tepper PG, Dijkstra D, Damsma G, Wikström H, Pugsley TA, Akunne HC, Heffner TG, Glase SA, Wise LD. van Vliet LA, et al. Among authors: dijkstra d. J Med Chem. 1996 Oct 11;39(21):4233-7. doi: 10.1021/jm960345l. J Med Chem. 1996. PMID: 8863800

8

Synthesis and pharmacological evaluation of thiopyran analogues of the dopamine D3 receptor-selective agonist (4aR,10bR)-(+)-trans-3,4,4a,10b-tetrahydro-4-n-propyl-2H,5H [1]b enzopyrano[4,3-b]-1,4-oxazin-9-ol (PD 128907).

van Vliet LA, Rodenhuis N, Dijkstra D, Wikström H, Pugsley TA, Serpa KA, Meltzer LT, Heffner TG, Wise LD, Lajiness ME, Huff RM, Svensson K, Sundell S, Lundmark M. van Vliet LA, et al. Among authors: dijkstra d. J Med Chem. 2000 Jul 27;43(15):2871-82. doi: 10.1021/jm0000113. J Med Chem. 2000. PMID: 10956195

9

Pharmacological aspects of R-(+)-7-OH-DPAT, a putative dopamine D3 receptor ligand.

Damsma G, Bottema T, Westerink BH, Tepper PG, Dijkstra D, Pugsley TA, MacKenzie RG, Heffner TG, Wikström H. Damsma G, et al. Among authors: dijkstra d. Eur J Pharmacol. 1993 Nov 16;249(3):R9-10. doi: 10.1016/0014-2999(93)90533-n. Eur J Pharmacol. 1993. PMID: 8287911

10

Characterization of the effect of dopamine D3 receptor stimulation on locomotion and striatal dopamine levels.

De Boer P, Enrico P, Wright J, Wise LD, Timmerman W, Moor E, Dijkstra D, Wikström HV, Westerink BH. De Boer P, et al. Among authors: dijkstra d. Brain Res. 1997 May 30;758(1-2):83-91. doi: 10.1016/s0006-8993(96)01438-2. Brain Res. 1997. PMID: 9203536

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