Tytgat J - Search Results

1

kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity.

Srinivasan KN, Sivaraja V, Huys I, Sasaki T, Cheng B, Kumar TK, Sato K, Tytgat J, Yu C, San BC, Ranganathan S, Bowie HJ, Kini RM, Gopalakrishnakone P. Srinivasan KN, et al. Among authors: tytgat j. J Biol Chem. 2002 Aug 16;277(33):30040-7. doi: 10.1074/jbc.M111258200. Epub 2002 May 28. J Biol Chem. 2002. PMID: 12034709 Free article.

2

The alpha-dendrotoxin footprint on a mammalian potassium channel.

Tytgat J, Debont T, Carmeliet E, Daenens P. Tytgat J, et al. J Biol Chem. 1995 Oct 20;270(42):24776-81. doi: 10.1074/jbc.270.42.24776. J Biol Chem. 1995. PMID: 7559595 Free article.

3

Electrophysiological characterization of BmK M1, an alpha-like toxin from Buthus martensi Karsch venom.

Goudet C, Huys I, Clynen E, Schoofs L, Wang DC, Waelkens E, Tytgat J. Goudet C, et al. Among authors: tytgat j. FEBS Lett. 2001 Apr 20;495(1-2):61-5. doi: 10.1016/s0014-5793(01)02365-1. FEBS Lett. 2001. PMID: 11322948 Free article.

4

OsK2, a new selective inhibitor of Kv1.2 potassium channels purified from the venom of the scorpion Orthochirus scrobiculosus.

Dudina EE, Korolkova YV, Bocharova NE, Koshelev SG, Egorov TA, Huys I, Tytgat J, Grishin EV. Dudina EE, et al. Among authors: tytgat j. Biochem Biophys Res Commun. 2001 Sep 7;286(5):841-7. doi: 10.1006/bbrc.2001.5492. Biochem Biophys Res Commun. 2001. PMID: 11527374

5

Purification, characterization and biosynthesis of parabutoxin 3, a component of Parabuthus transvaalicus venom.

Huys I, Dyason K, Waelkens E, Verdonck F, van Zyl J, du Plessis J, Müller GJ, van der Walt J, Clynen E, Schoofs L, Tytgat J. Huys I, et al. Among authors: tytgat j. Eur J Biochem. 2002 Apr;269(7):1854-65. doi: 10.1046/j.1432-1033.2002.02833.x. Eur J Biochem. 2002. PMID: 11952787 Free article.

6

A novel conotoxin from Conus betulinus, kappa-BtX, unique in cysteine pattern and in function as a specific BK channel modulator.

Fan CX, Chen XK, Zhang C, Wang LX, Duan KL, He LL, Cao Y, Liu SY, Zhong MN, Ulens C, Tytgat J, Chen JS, Chi CW, Zhou Z. Fan CX, et al. Among authors: tytgat j. J Biol Chem. 2003 Apr 11;278(15):12624-33. doi: 10.1074/jbc.M210200200. Epub 2003 Jan 23. J Biol Chem. 2003. PMID: 12547831 Free article.

7

Importance of the conserved aromatic residues in the scorpion alpha-like toxin BmK M1: the hydrophobic surface region revisited.

Sun YM, Bosmans F, Zhu RH, Goudet C, Xiong YM, Tytgat J, Wang DC. Sun YM, et al. Among authors: tytgat j. J Biol Chem. 2003 Jun 27;278(26):24125-31. doi: 10.1074/jbc.M211931200. Epub 2003 Apr 13. J Biol Chem. 2003. PMID: 12692120 Free article.

8

Evidence for a function-specific mutation in the neurotoxin, parabutoxin 3.

Huys I, Tytgat J. Huys I, et al. Among authors: tytgat j. Eur J Neurosci. 2003 May;17(9):1786-92. doi: 10.1046/j.1460-9568.2003.02613.x. Eur J Neurosci. 2003. PMID: 12752777

9

A novel conotoxin inhibiting vertebrate voltage-sensitive potassium channels.

Kauferstein S, Huys I, Lamthanh H, Stöcklin R, Sotto F, Menez A, Tytgat J, Mebs D. Kauferstein S, et al. Among authors: tytgat j. Toxicon. 2003 Jul;42(1):43-52. doi: 10.1016/s0041-0101(03)00099-0. Toxicon. 2003. PMID: 12893060

10

A subfamily of acidic alpha-K(+) toxins.

Huys I, Olamendi-Portugal T, Garcia-Gómez BI, Vandenberghe I, Van Beeumen J, Dyason K, Clynen E, Zhu S, van der Walt J, Possani LD, Tytgat J. Huys I, et al. Among authors: tytgat j. J Biol Chem. 2004 Jan 23;279(4):2781-9. doi: 10.1074/jbc.M311029200. Epub 2003 Oct 14. J Biol Chem. 2004. PMID: 14561751 Free article.

Analysis of the primary sequences reveals that they structurally belong to subfamily 11 of short chain alpha-K(+)-blocking peptides (Tytgat, J., Chandy, K. G., Garcia, M. L., Gutman, G. A., Martin-Eauclaire, M. F., van der Walt, J. J., and Possani, L. …

Analysis of the primary sequences reveals that they structurally belong to subfamily 11 of short chain alpha-K(+)-blocking peptides (Tytg …

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