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The MEK1/2-inhibitor ATR-002 efficiently blocks SARS-CoV-2 propagation and alleviates pro-inflammatory cytokine/chemokine responses.
Schreiber A, Viemann D, Schöning J, Schloer S, Mecate Zambrano A, Brunotte L, Faist A, Schöfbänker M, Hrincius E, Hoffmann H, Hoffmann M, Pöhlmann S, Rescher U, Planz O, Ludwig S. Schreiber A, et al. Among authors: ludwig s. Cell Mol Life Sci. 2022 Jan 10;79(1):65. doi: 10.1007/s00018-021-04085-1. Cell Mol Life Sci. 2022. PMID: 35013790 Free PMC article.
Targeting the endolysosomal host-SARS-CoV-2 interface by clinically licensed functional inhibitors of acid sphingomyelinase (FIASMA) including the antidepressant fluoxetine.
Schloer S, Brunotte L, Goretzko J, Mecate-Zambrano A, Korthals N, Gerke V, Ludwig S, Rescher U. Schloer S, et al. Among authors: ludwig s. Emerg Microbes Infect. 2020 Dec;9(1):2245-2255. doi: 10.1080/22221751.2020.1829082. Emerg Microbes Infect. 2020. PMID: 32975484 Free PMC article.
987 results