Goodwin B - Search Results

1

Nuclear receptors. I. Nuclear receptors and bile acid homeostasis.

Goodwin B, Kliewer SA. Goodwin B, et al. Am J Physiol Gastrointest Liver Physiol. 2002 Jun;282(6):G926-31. doi: 10.1152/ajpgi.00044.2002. Am J Physiol Gastrointest Liver Physiol. 2002. PMID: 12016116 Free article. Review.

2

Nuclear pregnane x receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification.

Maglich JM, Stoltz CM, Goodwin B, Hawkins-Brown D, Moore JT, Kliewer SA. Maglich JM, et al. Among authors: goodwin b. Mol Pharmacol. 2002 Sep;62(3):638-46. doi: 10.1124/mol.62.3.638. Mol Pharmacol. 2002. PMID: 12181440

3

The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.

Kliewer SA, Goodwin B, Willson TM. Kliewer SA, et al. Among authors: goodwin b. Endocr Rev. 2002 Oct;23(5):687-702. doi: 10.1210/er.2001-0038. Endocr Rev. 2002. PMID: 12372848 Review.

4

Nuclear receptor regulation of genes involved in bile acid metabolism.

Moore JT, Goodwin B, Willson TM, Kliewer SA. Moore JT, et al. Among authors: goodwin b. Crit Rev Eukaryot Gene Expr. 2002;12(2):119-35. doi: 10.1615/critreveukaryotgeneexpr.v12.i2.30. Crit Rev Eukaryot Gene Expr. 2002. PMID: 12434926 Review.

5

Identification of bile acid precursors as endogenous ligands for the nuclear xenobiotic pregnane X receptor.

Goodwin B, Gauthier KC, Umetani M, Watson MA, Lochansky MI, Collins JL, Leitersdorf E, Mangelsdorf DJ, Kliewer SA, Repa JJ. Goodwin B, et al. Proc Natl Acad Sci U S A. 2003 Jan 7;100(1):223-8. doi: 10.1073/pnas.0237082100. Epub 2002 Dec 30. Proc Natl Acad Sci U S A. 2003. PMID: 12509506 Free PMC article.

6

Differential regulation of rat and human CYP7A1 by the nuclear oxysterol receptor liver X receptor-alpha.

Goodwin B, Watson MA, Kim H, Miao J, Kemper JK, Kliewer SA. Goodwin B, et al. Mol Endocrinol. 2003 Mar;17(3):386-94. doi: 10.1210/me.2002-0246. Epub 2002 Dec 12. Mol Endocrinol. 2003. PMID: 12554795

7

Definition of a novel growth factor-dependent signal cascade for the suppression of bile acid biosynthesis.

Holt JA, Luo G, Billin AN, Bisi J, McNeill YY, Kozarsky KF, Donahee M, Wang DY, Mansfield TA, Kliewer SA, Goodwin B, Jones SA. Holt JA, et al. Among authors: goodwin b. Genes Dev. 2003 Jul 1;17(13):1581-91. doi: 10.1101/gad.1083503. Epub 2003 Jun 18. Genes Dev. 2003. PMID: 12815072 Free PMC article.

8

Regulation of cyp3a gene transcription by the pregnane x receptor.

Goodwin B, Redinbo MR, Kliewer SA. Goodwin B, et al. Annu Rev Pharmacol Toxicol. 2002;42:1-23. doi: 10.1146/annurev.pharmtox.42.111901.111051. Annu Rev Pharmacol Toxicol. 2002. PMID: 11807162 Review.

9

A regulatory cascade of the nuclear receptors FXR, SHP-1, and LRH-1 represses bile acid biosynthesis.

Goodwin B, Jones SA, Price RR, Watson MA, McKee DD, Moore LB, Galardi C, Wilson JG, Lewis MC, Roth ME, Maloney PR, Willson TM, Kliewer SA. Goodwin B, et al. Mol Cell. 2000 Sep;6(3):517-26. doi: 10.1016/s1097-2765(00)00051-4. Mol Cell. 2000. PMID: 11030332 Free article.

10

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.

Staudinger JL, Goodwin B, Jones SA, Hawkins-Brown D, MacKenzie KI, LaTour A, Liu Y, Klaassen CD, Brown KK, Reinhard J, Willson TM, Koller BH, Kliewer SA. Staudinger JL, et al. Among authors: goodwin b. Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3369-74. doi: 10.1073/pnas.051551698. Proc Natl Acad Sci U S A. 2001. PMID: 11248085 Free PMC article.

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