Irving PE - Search Results

1

2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: the discovery of alpha1a subtype selective 2'-alkylsulfonyl-substituted analogues.

Hodson SJ, Bishop MJ, Speake JD, Navas F 3rd, Garrison DT, Bigham EC, Saussy DL Jr, Liacos JA, Irving PE, Gobel MJ, Sherman BW. Hodson SJ, et al. Among authors: irving pe. J Med Chem. 2002 May 23;45(11):2229-39. doi: 10.1021/jm000542r. J Med Chem. 2002. PMID: 12014961

2

alpha(1)-Adrenoceptor agonists: the identification of novel alpha(1A )subtype selective 2'-heteroaryl-2-(phenoxymethyl)imidazolines.

Bishop MJ, Barvian KA, Berman J, Bigham EC, Garrison DT, Gobel MJ, Hodson SJ, Irving PE, Liacos JA, Navas F 3rd, Saussy DL, Speake JD. Bishop MJ, et al. Among authors: irving pe. Bioorg Med Chem Lett. 2002 Feb 11;12(3):471-5. doi: 10.1016/s0960-894x(01)00764-8. Bioorg Med Chem Lett. 2002. PMID: 11814822

3

2-(anilinomethyl)imidazolines as alpha1A adrenergic receptor agonists: 2'-heteroaryl and 2'-oxime ether series.

Navas F 3rd, Bishop MJ, Garrison DT, Hodson SJ, Speake JD, Bigham EC, Drewry DH, Saussy DL, Liacos JH, Irving PE, Gobel MJ. Navas F 3rd, et al. Among authors: irving pe. Bioorg Med Chem Lett. 2002 Feb 25;12(4):575-9. doi: 10.1016/s0960-894x(01)00822-8. Bioorg Med Chem Lett. 2002. PMID: 11844675

4

Alpha(1)-adrenoceptor activation: a comparison of 4-(anilinomethyl)imidazoles and 4-(phenoxymethyl)imidazoles to related 2-imidazolines.

Hodson SJ, Bigham EC, Garrison DT, Gobel MJ, Irving PE, Liacos JA, Navas F 3rd, Saussy DL Jr, Sherman BW, Speake JD, Bishop MJ. Hodson SJ, et al. Among authors: irving pe. Bioorg Med Chem Lett. 2002 Dec 2;12(23):3449-52. doi: 10.1016/s0960-894x(02)00753-9. Bioorg Med Chem Lett. 2002. PMID: 12419381

5

2-(Anilinomethyl)imidazolines as alpha1 adrenergic receptor agonists: alpha1a subtype selective 2'-heteroaryl compounds.

Speake JD, Navas F, Bishop MJ, Garrison DT, Bigham EC, Hodson SJ, Saussy DL, Liacos JA, Irving PE, Sherman BW. Speake JD, et al. Among authors: irving pe. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1183-6. doi: 10.1016/s0960-894x(03)00050-7. Bioorg Med Chem Lett. 2003. PMID: 12643939

6

2-(Anilinomethyl)imidazolines as alpha(1)-adrenoceptor agonists: the identification of alpha(1A) subtype selective 2'-carboxylic acid esters and amides.

Bishop MJ, Berman J, Bigham EC, Garrison DT, Gobel MJ, Hodson SJ, Irving PE, Liacos JA, Minick DJ, Navas F, Saussy DL Jr, Speake JD. Bishop MJ, et al. Among authors: irving pe. Bioorg Med Chem Lett. 2001 Nov 5;11(21):2871-4. doi: 10.1016/s0960-894x(01)00569-8. Bioorg Med Chem Lett. 2001. PMID: 11597419

7

The use of stimulus-biased assay systems to detect agonist-specific receptor active states: implications for the trafficking of receptor stimulus by agonists.

Watson C, Chen G, Irving P, Way J, Chen WJ, Kenakin T. Watson C, et al. Mol Pharmacol. 2000 Dec;58(6):1230-8. doi: 10.1124/mol.58.6.1230. Mol Pharmacol. 2000. PMID: 11093758

8

The relative efficiency of beta adrenoceptor coupling to myocardial inotropy and diastolic relaxation: organ-selective treatment for diastolic dysfunction.

Kenakin TP, Ambrose JR, Irving PE. Kenakin TP, et al. Among authors: irving pe. J Pharmacol Exp Ther. 1991 Jun;257(3):1189-97. J Pharmacol Exp Ther. 1991. PMID: 1675290

9

Expression cloning and receptor pharmacology of human calcitonin receptors from MCF-7 cells and their relationship to amylin receptors.

Chen WJ, Armour S, Way J, Chen G, Watson C, Irving P, Cobb J, Kadwell S, Beaumont K, Rimele T, Kenakin T. Chen WJ, et al. Mol Pharmacol. 1997 Dec;52(6):1164-75. doi: 10.1124/mol.52.6.1164. Mol Pharmacol. 1997. PMID: 9396787

10

A mathematical model for analysis of pharmacologically induced changes in the kinetics of cardiac muscle.

Lutz MW, Morgan PH, Kenakin TP, Goetz A, Queen K, Irving P, Rose D, Gill JM, Rimele T. Lutz MW, et al. J Pharmacol Toxicol Methods. 1996 Nov;36(3):171-83. doi: 10.1016/s1056-8719(96)00114-1. J Pharmacol Toxicol Methods. 1996. PMID: 8959583

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